Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50005473
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037287((1S,3S,4S,5R,6R,7R)-1-((4S,5S)-4-Acetoxy-3,5-dimet...)
Affinity DataIC50: 3nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037287((1S,3S,4S,5R,6R,7R)-1-((4S,5S)-4-Acetoxy-3,5-dimet...)
Affinity DataIC50: 3nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037286((1S,3S,4S,5R,6R,7R)-1-((4R,5S)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 5nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037285((1S,3S,4S,5R,6R,7R)-6-((E)-(4S,6S)-4,6-Dimethyl-oc...)
Affinity DataIC50: 5nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037287((1S,3S,4S,5R,6R,7R)-1-((4S,5S)-4-Acetoxy-3,5-dimet...)
Affinity DataIC50: 7nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037287((1S,3S,4S,5R,6R,7R)-1-((4S,5S)-4-Acetoxy-3,5-dimet...)
Affinity DataIC50: 7nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037279((1S,3S,4S,5R,6R,7R)-6-((4R,6S)-4,6-Dimethyl-octano...)
Affinity DataIC50: 8nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037279((1S,3S,4S,5R,6R,7R)-6-((4R,6S)-4,6-Dimethyl-octano...)
Affinity DataIC50: 9nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037286((1S,3S,4S,5R,6R,7R)-1-((4R,5S)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037289((1S,3S,4S,5R,6R,7R)-1-((4R,5S)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037291((1S,3S,4S,5R,6R,7R)-6-((4R,6S)-4,6-Dimethyl-octano...)
Affinity DataIC50: 13nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037291((1S,3S,4S,5R,6R,7R)-6-((4R,6S)-4,6-Dimethyl-octano...)
Affinity DataIC50: 14nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037290((1S,3S,4S,5R,6R,7R)-1-((E)-(4R,5S)-4-Acetoxy-3,5-d...)
Affinity DataIC50: 22nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037280((1S,3S,4S,5R,6R,7R)-1-((4R,5S)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037288((1S,3S,4S,5R,6R,7R)-6-((E)-(4S,6S)-4,6-Dimethyl-oc...)
Affinity DataIC50: 32nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037282((1S,3S,4S,5R,6R,7R)-6-((E)-(4S,6S)-4,6-Dimethyl-oc...)
Affinity DataIC50: 65nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037284((1S,3S,4S,5R,6R,7R)-1-((4S,5S)-4-Acetoxy-3,5-dimet...)
Affinity DataIC50: 143nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037284((1S,3S,4S,5R,6R,7R)-1-((4S,5S)-4-Acetoxy-3,5-dimet...)
Affinity DataIC50: 200nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037283((1S,3S,4S,5R,6R,7R)-1-((E)-(S)-3,5-Dimethyl-6-phen...)
Affinity DataIC50: 200nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037281((1S,3S,4S,5R,6R,7R)-1-((R)-3,5-Dimethyl-6-phenyl-h...)
Affinity DataIC50: 200nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037283((1S,3S,4S,5R,6R,7R)-1-((E)-(S)-3,5-Dimethyl-6-phen...)
Affinity DataIC50: 208nMAssay Description:Compound was tested for in vitro inhibitory activity against Candida albicans 2005E microsomal SQSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037292((1S,3S,4S,5R,6R,7R)-4,6,7-Trihydroxy-1-((4R,5S)-4-...)
Affinity DataIC50: 252nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Glaxo Research and Development

Curated by ChEMBL
LigandPNGBDBM50037281((1S,3S,4S,5R,6R,7R)-1-((R)-3,5-Dimethyl-6-phenyl-h...)
Affinity DataIC50: 415nMAssay Description:Inhibition of juvenile male rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed