Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50005477
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037338({6-(3-Chloro-phenyl)-2-oxo-1-[(3,3,3-trifluoro-1-i...)
Affinity DataKi:  3.5nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037340({6-(3,5-Dimethoxy-phenyl)-2-oxo-1-[(3,3,3-trifluor...)
Affinity DataKi:  3.80nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037333({6-(3-tert-Butoxy-phenyl)-2-oxo-1-[(3,3,3-trifluor...)
Affinity DataKi:  4.40nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50036127({2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  4.5nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037327({6-(3-Hydroxy-phenyl)-2-oxo-1-[(3,3,3-trifluoro-1-...)
Affinity DataKi:  5.60nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037325({6-(4-Chloro-phenyl)-2-oxo-1-[(3,3,3-trifluoro-1-i...)
Affinity DataKi:  6.60nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037339({6-(4-Methoxy-phenyl)-2-oxo-1-[(3,3,3-trifluoro-1-...)
Affinity DataKi:  8.5nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037335({6-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propy...)
Affinity DataKi:  9.10nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037336({6-(2-Chloro-phenyl)-2-oxo-1-[(3,3,3-trifluoro-1-i...)
Affinity DataKi:  11nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037329({2-Oxo-6-p-tolyl-1-[(3,3,3-trifluoro-1-isopropyl-2...)
Affinity DataKi:  31nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037326(3-{5-Benzyloxycarbonylamino-6-oxo-1-[(3,3,3-triflu...)
Affinity DataKi:  32nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037330({2-Oxo-6-((E)-styryl)-1-[(3,3,3-trifluoro-1-isopro...)
Affinity DataKi:  33nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037110({5-Benzyl-2-oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  40nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037331(4-{5-Benzyloxycarbonylamino-6-oxo-1-[(3,3,3-triflu...)
Affinity DataKi:  42nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50036127({2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  55nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037334({6-Benzyl-2-oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  66nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037324({2-Oxo-6-phenethyl-1-[(3,3,3-trifluoro-1-isopropyl...)
Affinity DataKi:  79nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037109({2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propy...)
Affinity DataKi:  280nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037332({2-Oxo-5-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  300nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037328({2-Oxo-4-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  320nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037337({6-Methyl-2-oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  360nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037325({6-(4-Chloro-phenyl)-2-oxo-1-[(3,3,3-trifluoro-1-i...)
Affinity DataKi:  500nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037329({2-Oxo-6-p-tolyl-1-[(3,3,3-trifluoro-1-isopropyl-2...)
Affinity DataKi:  720nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-like elastase family member 2A(Pig)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50036127({2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibitory activity against porcine pancreatic elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50036127({2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  4.80E+3nMAssay Description:Inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037330({2-Oxo-6-((E)-styryl)-1-[(3,3,3-trifluoro-1-isopro...)
Affinity DataKi:  5.80E+3nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037110({5-Benzyl-2-oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  6.20E+3nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPapain(Papaya)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50036127({2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibitory activity against papainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037324({2-Oxo-6-phenethyl-1-[(3,3,3-trifluoro-1-isopropyl...)
Affinity DataKi:  9.60E+3nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Zeneca Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50037109({2-Oxo-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propy...)
Affinity DataKi:  3.30E+5nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed