Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50005616
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038733(Hexyl-carbamic acid (3aS,8aR)-1-ethyl-3a-methyl-1,...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038740(Hexyl-carbamic acid 9-methyl-9-aza-tricyclo[6.3.1....)
Affinity DataIC50: 72nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10972((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038740(Hexyl-carbamic acid 9-methyl-9-aza-tricyclo[6.3.1....)
Affinity DataIC50: 122nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 5.0 mg/kg via peroral administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038732(Hexyl-carbamic acid 9-ethyl-9-aza-tricyclo[6.3.1.0...)
Affinity DataIC50: 125nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 128nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038736(Hexyl-carbamic acid 9-ethyl-1-methyl-9-aza-tricycl...)
Affinity DataIC50: 133nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038731(1,2,3,4-Tetrahydro-acridine | CHEMBL292518)
Affinity DataIC50: 136nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 6.6 mg/kg via intraperitoneal administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038734(Heptyl-carbamic acid 9-methyl-9-aza-tricyclo[6.3.1...)
Affinity DataIC50: 143nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM10972((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 148nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 4.8 mg/kg via intraperitoneal administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038740(Hexyl-carbamic acid 9-methyl-9-aza-tricyclo[6.3.1....)
Affinity DataIC50: 148nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 1.2 mg/kg via intraperitoneal administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038733(Hexyl-carbamic acid (3aS,8aR)-1-ethyl-3a-methyl-1,...)
Affinity DataIC50: 148nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 0.8 mg/kg via intraperitoneal administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038738(Heptyl-carbamic acid 9-ethyl-9-aza-tricyclo[6.3.1....)
Affinity DataIC50: 153nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 4.4 mg/kg via intraperitoneal administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038732(Hexyl-carbamic acid 9-ethyl-9-aza-tricyclo[6.3.1.0...)
Affinity DataIC50: 156nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 1.8 mg/kg via intraperitoneal administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038734(Heptyl-carbamic acid 9-methyl-9-aza-tricyclo[6.3.1...)
Affinity DataIC50: 159nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 3.6 mg/kg via intraperitoneal administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038737(Heptyl-carbamic acid 9-ethyl-1-methyl-9-aza-tricyc...)
Affinity DataIC50: 159nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038738(Heptyl-carbamic acid 9-ethyl-9-aza-tricyclo[6.3.1....)
Affinity DataIC50: 169nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038735(Methyl-carbamic acid 9-ethyl-9-aza-tricyclo[6.3.1....)
Affinity DataIC50: 171nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50038739(Butyl-carbamic acid 9-ethyl-9-aza-tricyclo[6.3.1.0...)
Affinity DataIC50: 206nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed