Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50005630
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000293(2-(3,4-Dichloro-phenyl)-1-(7-pyrrolidin-1-ylmethyl...)
Affinity DataIC50: 0.100nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50001107(CHEMBL66018 | CHEMBL554426 | 2-(3,4-Dichloro-pheny...)
Affinity DataIC50: 0.110nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039101(2-(3,4-Dichloro-phenyl)-1-[4-(3-hydroxy-pyrrolidin...)
Affinity DataIC50: 0.390nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039104((SS)-2-(3,4-Dichloro-phenyl)-1-[4-(3-hydroxy-pyrro...)
Affinity DataIC50: 0.470nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039103(2-(3,4-Dichloro-phenyl)-1-[(R)-4-((S)-3-hydroxy-py...)
Affinity DataIC50: 1.10nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039097(2-(3,4-Dichloro-phenyl)-1-[4-(3,6-dihydro-2H-pyrid...)
Affinity DataIC50: 1.40nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039098(2-(3,4-Dichloro-phenyl)-1-[4-(3-hydroxy-pyrrolidin...)
Affinity DataIC50: 2.70nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039102((RS)-2-(3,4-Dichloro-phenyl)-1-[4-(3-hydroxy-pyrro...)
Affinity DataIC50: 3.40nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039100(2-(3,4-Dichloro-phenyl)-1-[5-hydroxy-1-(3-hydroxy-...)
Affinity DataIC50: 3.80nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039099(1-{5-[2-(3,4-Dichloro-phenyl)-acetyl]-4,5,6,7-tetr...)
Affinity DataIC50: 6nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039107(2-(3,4-Dichloro-phenyl)-1-(4-pyrrolidin-1-ylmethyl...)
Affinity DataIC50: 15nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039105(2-(3,4-Dichloro-phenyl)-1-(4-dimethylaminomethyl-6...)
Affinity DataIC50: 22nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50039104((SS)-2-(3,4-Dichloro-phenyl)-1-[4-(3-hydroxy-pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro kappa-opioid receptor agonist activity in isolated rabbit vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed