Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50005645
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  0.560nMAssay Description:Tested for binding affinity towards mu receptor in presence of [3H]NAL radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50039183({(S)-2-Benzyl-3-[4-(3-hydroxy-phenyl)-3,4-dimethyl...)
Affinity DataKi:  0.770nMAssay Description:Tested for binding affinity towards mu receptor in presence of [3H]NAL radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50039180({2-Benzyl-3-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dime...)
Affinity DataKi:  0.890nMAssay Description:Tested for binding affinity towards mu receptor in presence of [3H]NAL radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50039181(2-Benzyl-3-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dimet...)
Affinity DataKi:  2.60nMAssay Description:Tested for binding affinity towards mu receptor in presence of [3H]NAL radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  3.70nMAssay Description:Tested for binding affinity towards mu receptor in presence of [3H]NAL radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50453378(CHEMBL2114114)
Affinity DataKi:  4nMAssay Description:Tested for binding affinity towards mu receptor in presence of [3H]NAL radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50039183({(S)-2-Benzyl-3-[4-(3-hydroxy-phenyl)-3,4-dimethyl...)
Affinity DataKi:  4.40nMAssay Description:Tested for binding affinity towards delta receptor in rat brain homogenates using [3H]D-Ala2-D-Leu3-enkephalin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50453377(CHEMBL2115154)
Affinity DataKi:  5.5nMAssay Description:Tested for binding affinity towards mu receptor in presence of [3H]NAL radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  6nMAssay Description:Tested for binding affinity towards kappa receptor in presence of [3H]EKC radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50453377(CHEMBL2115154)
Affinity DataKi:  23nMAssay Description:Tested for binding affinity towards kappa receptor in presence of [3H]EKC radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50039183({(S)-2-Benzyl-3-[4-(3-hydroxy-phenyl)-3,4-dimethyl...)
Affinity DataKi:  40nMAssay Description:Tested for binding affinity towards kappa receptor in presence of [3H]EKC radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  66nMAssay Description:Tested for binding affinity towards kappa receptor in presence of [3H]EKC radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed