Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50005651
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataIC50: 300nMAssay Description:Tested for its inhibitory activity against HMG-CoA reductase transcription in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50039254(4-{(E)-2-[3-(5-Hydroxy-5-methyl-hexyl)-phenyl]-vin...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for its inhibitory activity against HMG-CoA reductase transcription in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed