Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50005698
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039998([(S)-1-((S)-1-Ethylcarbamoyl-butylcarbamoyl)-3-met...)
Affinity DataKi:  32nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  35nMAssay Description:Tested for inhibitory activity on human calpain 2 from placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040007([(S)-1-((S)-1-Ethylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi:  36nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Bovine)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  40nMAssay Description:Tested for inhibitory activity on bovine calpain 2 from heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994([(S)-1-(1-Ethylcarbamoyl-butylcarbamoyl)-3-methyl-...)
Affinity DataKi:  42nMAssay Description:Tested for inhibitory activity on porcine calpain 2 from kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Bovine)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994([(S)-1-(1-Ethylcarbamoyl-butylcarbamoyl)-3-methyl-...)
Affinity DataKi:  50nMAssay Description:Tested for inhibitory activity on bovine calpain 2 from heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  51nMAssay Description:Tested for inhibitory activity on porcine calpain 2 from kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040009({(S)-1-[(S)-1-((S)-1-Ethylcarbamoyl-butylcarbamoyl...)
Affinity DataKi:  61nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994([(S)-1-(1-Ethylcarbamoyl-butylcarbamoyl)-3-methyl-...)
Affinity DataKi:  66nMAssay Description:Tested for inhibitory activity on human calpain 1 from erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994([(S)-1-(1-Ethylcarbamoyl-butylcarbamoyl)-3-methyl-...)
Affinity DataKi:  73nMAssay Description:Tested for inhibitory activity on human calpain 2 from placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  74nMAssay Description:Tested for inhibitory activity on human calpain 1 from erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994([(S)-1-(1-Ethylcarbamoyl-butylcarbamoyl)-3-methyl-...)
Affinity DataKi:  78nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039994([(S)-1-(1-Ethylcarbamoyl-butylcarbamoyl)-3-methyl-...)
Affinity DataKi:  78nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  89nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039995([(S)-1-(1-Ethylcarbamoyl-2-phenyl-ethylcarbamoyl)-...)
Affinity DataKi:  89nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039999((S)-2-[(R)-3-((S)-2-Benzyloxycarbonylamino-4-methy...)
Affinity DataKi:  92nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040000({(R)-1-[(S)-1-((S)-1-Ethylcarbamoyl-butylcarbamoyl...)
Affinity DataKi:  93nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993([(S)-1-(3-Ethylcarbamoyl-propylcarbamoyl)-3-methyl...)
Affinity DataKi:  109nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993([(S)-1-(3-Ethylcarbamoyl-propylcarbamoyl)-3-methyl...)
Affinity DataKi:  109nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040001((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-meth...)
Affinity DataKi:  116nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039996(Morpholine-4-carboxylic acid [(S)-1-(3-ethylcarbam...)
Affinity DataKi:  119nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993([(S)-1-(3-Ethylcarbamoyl-propylcarbamoyl)-3-methyl...)
Affinity DataKi:  122nMAssay Description:Tested for inhibitory activity on bovine calpain 2 from heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040004({(S)-1-[(R)-1-Benzyl-2-(2-ethanesulfonyl-ethylcarb...)
Affinity DataKi:  129nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993([(S)-1-(3-Ethylcarbamoyl-propylcarbamoyl)-3-methyl...)
Affinity DataKi:  138nMAssay Description:Tested for inhibitory activity on human calpain II from placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Bovine)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993([(S)-1-(3-Ethylcarbamoyl-propylcarbamoyl)-3-methyl...)
Affinity DataKi:  138nMAssay Description:Tested for inhibitory activity on bovine calpain II from heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040008([(S)-1-(3-Ethylcarbamoyl-propylcarbamoyl)-3-methyl...)
Affinity DataKi:  170nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039993([(S)-1-(3-Ethylcarbamoyl-propylcarbamoyl)-3-methyl...)
Affinity DataKi:  210nMAssay Description:Tested for inhibitory activity on human calpain 1 from erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040002((S)-2-((R)-2-Amino-3-phenyl-propionylamino)-4-meth...)
Affinity DataKi:  244nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50039997((S)-2-(3,3-Dimethyl-ureido)-4-methyl-pentanoic aci...)
Affinity DataKi:  333nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040005((S)-2-[(R)-3-((S)-2-Benzyloxycarbonylamino-4-methy...)
Affinity DataKi:  718nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040006([(S)-1-((R)-1-Ethylcarbamoyl-2-phenyl-ethylcarbamo...)
Affinity DataKi: >1.50E+3nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Alkermes

Curated by ChEMBL
LigandPNGBDBM50040003([(S)-1-((R)-1-Benzyl-2-ethylcarbamoyl-2-hydroxy-et...)
Affinity DataKi: >3.50E+5nMAssay Description:In vitro inhibition of porcine erythrocyte calpain 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed