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Found
110
Enz. Inhib. hit(s) with all data for entry = 4918
Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50001714
(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-ox...)
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Affinity Data
Ki: 0.0100nM
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In Depth
Date in BDB:
1/2/2012
Entry Details
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82552
(CAS_111555-58-9 | naltrindolebenzofuran | NTB)
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Ki: 0.0100nM
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Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50039022
(BW373U86 | CHEMBL69052 | 4-[(S)-((2R,5S)-4-Allyl-2...)
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Ki: 0.0100nM
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Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM21864
(NALTRINDOLE | (8R)-7-(cyclopropylmethyl)-5,6,7,8,1...)
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Ki: 0.0200nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82551
(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
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Affinity Data
Ki: 0.0200nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM83436
(2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-py...)
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Ki: 0.0300nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82555
(CAS_4424 | NSC_4424 | Naloxonazine)
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Ki: 0.0500nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50001714
(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-ox...)
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Ki: 0.0700nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82427
(CAS_5985-38-6 | LEVORPHANOL-tartarate)
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Ki: 0.0800nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50013388
(CHEMBL350384 | BREMAZOCINE(-) | 6-Ethyl-3-(1-hydro...)
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Ki: 0.0800nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82554
(CAS_115070 | NSC_115070 | Beta C N A)
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Ki: 0.0800nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50169774
(CHEMBL360943 | U50,488H | U-50488H | 2-(3,4-Dichlo...)
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Ki: 0.120nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82425
(NSC_61677 | CAS_61677 | ETORPHINE - HCI)
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Affinity Data
Ki: 0.130nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM94503
(N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl)piper...)
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Ki: 0.150nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50019574
(CTOP | CHEMBL406014 | D-Phe-Cys-Tyr-D-Trp-Orn-Thr-...)
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Ki: 0.180nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82425
(NSC_61677 | CAS_61677 | ETORPHINE - HCI)
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Affinity Data
Ki: 0.230nM
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Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50001714
(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-ox...)
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Ki: 0.230nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82553
(BETA-FUNALTREXAMINE | CAS_72786-10-8 | b-FNA-HCl)
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Affinity Data
Ki: 0.330nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82550
(NSC_125954 | CAS_118476-87-2 | Dermorphin)
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Ki: 0.330nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50008984
(N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionami...)
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Affinity Data
Ki: 0.390nM
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Date in BDB:
1/2/2012
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3D Structure (crystal)
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50000091
(EKC | EKC(-) | CHEMBL279968 | 3-Cyclopropylmethyl-...)
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Affinity Data
Ki: 0.400nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50010702
(Dynorphin A (1-17) | dynorphin A | DYNORPHIN(1-17)...)
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Ki: 0.5nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM21130
(U69,593 | N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspir...)
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Ki: 0.590nM
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In Depth
Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50019056
(2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
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Ki: 0.650nM
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Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50040485
(15-benzyl-4-cyclopropylmethyl-10,17-dihydroxy-(1S,...)
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Ki: 0.660nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82507
(CAS_5967-73-7 | NSC_22266 | METHADONE | Methadone-...)
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Ki: 0.720nM
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Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM21025
([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...)
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Ki: 0.740nM
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In Depth
Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50013388
(CHEMBL350384 | BREMAZOCINE(-) | 6-Ethyl-3-(1-hydro...)
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Affinity Data
Ki: 0.75nM
More data for this Ligand-Target Pair
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82554
(CAS_115070 | NSC_115070 | Beta C N A)
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Affinity Data
Ki: 0.900nM
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In Depth
Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50000788
([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
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Ki: 0.930nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50021560
(NALORPHINE - HCI | 4-allyl-(1S,13R,14S)-12-oxa-4-a...)
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Ki: 0.970nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM81934
(Beta-Endorphin)
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Ki: 1nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM60212
(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
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Ki: 1nM
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Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM81934
(Beta-Endorphin)
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Ki: 1nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50021560
(NALORPHINE - HCI | 4-allyl-(1S,13R,14S)-12-oxa-4-a...)
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Ki: 1.10nM
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In Depth
Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82425
(NSC_61677 | CAS_61677 | ETORPHINE - HCI)
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Affinity Data
Ki: 1.40nM
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In Depth
Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50045216
(7-spiroindanyloxymorphone | 7-(Spiroindano)Oxymorp...)
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Ki: 1.70nM
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In Depth
Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50019056
(2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
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Ki: 1.70nM
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In Depth
Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM21015
([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
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Ki: 2nM
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In Depth
Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82551
(C18130 | CAS_105618-26-6 | NORBNI | NOR-BNI (HCI)2)
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Ki: 2.20nM
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In Depth
Date in BDB:
1/2/2012
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Copy BDB DOI
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50000788
([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
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Ki: 2.30nM
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In Depth
Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50013388
(CHEMBL350384 | BREMAZOCINE(-) | 6-Ethyl-3-(1-hydro...)
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Ki: 2.30nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM82553
(BETA-FUNALTREXAMINE | CAS_72786-10-8 | b-FNA-HCl)
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Ki: 2.80nM
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Date in BDB:
1/2/2012
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50000091
(EKC | EKC(-) | CHEMBL279968 | 3-Cyclopropylmethyl-...)
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Ki: 3.10nM
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Date in BDB:
1/2/2012
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50000507
(Tyr-D-Ala-Phe-Glu-Val-Val-GlyNH2 | 4-(2-{2-[2-Amin...)
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Ki: 3.30nM
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In Depth
Date in BDB:
1/2/2012
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PubMed
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Target
Mu-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50001465
(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
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Ki: 3.40nM
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In Depth
Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50105085
(US9233167, Nalbuphine | 17-cyclobutylmethyl-4,5alp...)
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Ki: 3.90nM
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Date in BDB:
1/2/2012
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Target
Kappa-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM60212
(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
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Ki: 3.90nM
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/2/2012
Entry Details
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PubMed
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50001465
(2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
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Affinity Data
Ki: 4nM
More data for this Ligand-Target Pair
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Date in BDB:
1/2/2012
Entry Details
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Target
Delta-type opioid receptor
(Human)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM50018708
(DSLET-OH | DSLET | CHEMBL124283 | Tyr-D-Ser-Gly-Ph...)
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Ki: 4.80nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
1/2/2012
Entry Details
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