Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50036315
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16496(CHEMBL10413 | FR 74366 | [3-(4-bromo-2-fluorobenzy...)
Affinity DataIC50: 4.40nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50009777(Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50049730(Epalrestat | 2-(5-(2-methyl-3-phenylallylidene)-4-...)
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040782((2,8-Diisopropyl-3-thioxo-2,3-dihydro-benzo[1,4]ox...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040781((2,7-Difluoro-9H-fluoren-9-yl)-acetic acid | CHEMB...)
Affinity DataIC50: 430nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040779((2-Fluoro-9H-fluoren-9-yl)-acetic acid | CHEMBL349...)
Affinity DataIC50: 850nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16415((1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040780(cid_234512 | CHEMBL163958 | spiro[9H-fluorene-9,4'...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50034798((9H-Fluoren-9-yl)-acetic acid | CHEMBL44381)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040777(spiro[9H-fluorene-9,4'-(tetrahydro-1'H-imidazole)]...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040783((2,7-Difluoro-fluoren-9-ylidene)-acetic acid | CHE...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040784([2-Fluoro-fluoren-(9E)-ylidene]-acetic acid | CHEM...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50034811(9H-Fluorene-9-carboxylic acid | CHEMBL295321)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040778(5-(9H-Fluoren-9-yl)-1H-tetrazole | CHEMBL164508)
Affinity DataIC50: 2.17E+5nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50040785(5-(9H-Fluoren-9-ylmethyl)-1H-tetrazole | CHEMBL353...)
Affinity DataIC50: 1.49E+6nMAssay Description:Inhibitory activity against purified rat lens aldose reductase (RLAR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed