Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50036320
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453639(CHEMBL2112889)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041282((3S,8R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453639(CHEMBL2112889)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50035738(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453638(CHEMBL2112877)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453638(CHEMBL2112877)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041282((3S,8R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50012154(CHEMBL21112 | 3-(4-Fluoro-phenyl)-8-aza-bicyclo[3....)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041282((3S,8R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453639(CHEMBL2112889)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453640(CHEMBL2112860)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50451132(WIN-35428 | CHEMBL2079586)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50012154(CHEMBL21112 | 3-(4-Fluoro-phenyl)-8-aza-bicyclo[3....)
Affinity DataIC50: 19nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50118185(3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041281((3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carb...)
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50005576((3S,8R)-3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3...)
Affinity DataIC50: 36nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50035738(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50: 37nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50035738(3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453640(CHEMBL2112860)
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50118185(3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 55nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 67nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50012154(CHEMBL21112 | 3-(4-Fluoro-phenyl)-8-aza-bicyclo[3....)
Affinity DataIC50: 69nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041281((3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carb...)
Affinity DataIC50: 85nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 89nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453640(CHEMBL2112860)
Affinity DataIC50: 122nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041285((3S,8R)-3-Benzoyloxy-8-aza-bicyclo[3.2.1]octane-2-...)
Affinity DataIC50: 127nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50453638(CHEMBL2112877)
Affinity DataIC50: 132nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041285((3S,8R)-3-Benzoyloxy-8-aza-bicyclo[3.2.1]octane-2-...)
Affinity DataIC50: 139nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041281((3S,8R)-3-Phenyl-8-aza-bicyclo[3.2.1]octane-2-carb...)
Affinity DataIC50: 156nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50041285((3S,8R)-3-Benzoyloxy-8-aza-bicyclo[3.2.1]octane-2-...)
Affinity DataIC50: 206nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50006784(CHEMBL82946 | RTI-121 | 3-(4-Iodo-phenyl)-8-methyl...)
Affinity DataIC50: 285nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50451132(WIN-35428 | CHEMBL2079586)
Affinity DataIC50: 759nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50451132(WIN-35428 | CHEMBL2079586)
Affinity DataIC50: 834nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataIC50: 920nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50366564(CHEMBL1790051 | CHEMBL83729 | WIN-35065-2)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]paroxetine binding to 5-hydroxytryptamine (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50118185(3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 3.91E+3nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed