Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50005847
TargetEndothelin-1 receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041617((1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymet...)
Affinity DataKi:  0.430nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041616((1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-ph...)
Affinity DataKi:  11.3nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041617((1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymet...)
Affinity DataKi:  14.7nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041622((1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-5-hydroxy-3-(4-...)
Affinity DataKi:  15nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041618((1R,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-ph...)
Affinity DataKi:  43nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041621((1R,2R,3S)-1,3-Bis-(4-methoxy-phenyl)-indan-2-carb...)
Affinity DataKi:  422nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041622((1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-5-hydroxy-3-(4-...)
Affinity DataKi:  483nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041618((1R,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-ph...)
Affinity DataKi:  757nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041616((1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-ph...)
Affinity DataKi:  1.04E+3nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041621((1R,2R,3S)-1,3-Bis-(4-methoxy-phenyl)-indan-2-carb...)
Affinity DataKi:  2.44E+3nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041619((1S,2S,3R)-1-(4-Methoxy-phenyl)-3-phenyl-indan-2-c...)
Affinity DataKi:  5.67E+3nMAssay Description:Inhibition of [125I]ET1 binding to cloned human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041620((1R,2R,3S)-1,3-Diphenyl-indan-2-carboxylic acid | ...)
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041620((1R,2R,3S)-1,3-Diphenyl-indan-2-carboxylic acid | ...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041619((1S,2S,3R)-1-(4-Methoxy-phenyl)-3-phenyl-indan-2-c...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of [125I]ET1 binding to cloned human ET-B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed