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Found
41
Enz. Inhib. hit(s) with all data for entry = 4924
Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
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Affinity Data
Ki: 0.390nM
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Date in BDB:
1/2/2012
Entry Details
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Affinity Data
Ki: 0.930nM
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Date in BDB:
1/2/2012
Entry Details
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PDB
3D Structure (crystal)
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM78940
(methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-...)
Copy SMILES
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Affinity Data
Ki: 3.70nM
More data for this Ligand-Target Pair
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
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Affinity Data
Ki: 5nM
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Date in BDB:
1/2/2012
Entry Details
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50280055
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
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Affinity Data
Ki: 5.40nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM30704
(METERGOLINE | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7...)
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Affinity Data
Ki: 6.40nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Affinity Data
Ki: 8.10nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50280055
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
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Affinity Data
Ki: 9.20nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50001775
(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
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Affinity Data
Ki: 16nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50130269
(LSD,2-Bromo | (6aR,9R)-5-Bromo-7-methyl-4,6,6a,7,8...)
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Affinity Data
Ki: 17.1nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50024204
(MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...)
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Affinity Data
Ki: 18nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
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Affinity Data
Ki: 18nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50130269
(LSD,2-Bromo | (6aR,9R)-5-Bromo-7-methyl-4,6,6a,7,8...)
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Affinity Data
Ki: 30nM
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Date in BDB:
1/2/2012
Entry Details
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50001775
(cid_5074 | Ritanserine | 6-(2-{4-[Bis-(4-fluoro-ph...)
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Affinity Data
Ki: 45nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Affinity Data
Ki: 56nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM30704
(METERGOLINE | (phenylmethyl) N-[[(6aR,9S,10aR)-4,7...)
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Affinity Data
Ki: 61nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50031942
(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
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Affinity Data
Ki: 83nM
More data for this Ligand-Target Pair
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50007407
(CHEMBL277120 | 1-NP | 1-Naphthalen-1-yl-piperazine...)
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Affinity Data
Ki: 83nM
More data for this Ligand-Target Pair
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50007407
(CHEMBL277120 | 1-NP | 1-Naphthalen-1-yl-piperazine...)
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Affinity Data
Ki: 104nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
1/2/2012
Entry Details
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM21397
(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
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Affinity Data
Ki: 110nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50017721
(5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclop...)
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Affinity Data
Ki: 123nM
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1/2/2012
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50017721
(5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclop...)
Copy SMILES
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Affinity Data
Ki: 134nM
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50024210
(1H-indole-3-ethanamine | CHEMBL6640 | 2-(3-indolyl...)
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Affinity Data
Ki: 149nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 4
(Rat)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM10755
([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
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Affinity Data
Ki: 200nM
More data for this Ligand-Target Pair
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM21392
([3H]-5-carboxamidotryptamine | CHEMBL18840 | 5-car...)
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Affinity Data
Ki: 253nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 4
(Rat)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM82087
(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Copy SMILES
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Affinity Data
Ki: 316nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 4
(Rat)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50000492
(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
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Affinity Data
Ki: 316nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50031942
(CHEMBL1065 | Sansert | (6aR,9R)-4-Methyl-4,6,6a,7,...)
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Affinity Data
Ki: 372nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50024210
(1H-indole-3-ethanamine | CHEMBL6640 | 2-(3-indolyl...)
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Affinity Data
Ki: 438nM
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM21393
(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
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Affinity Data
Ki: 466nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50005835
(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
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Affinity Data
Ki: 951nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM21395
(3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}e...)
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Affinity Data
Ki: 1.33E+3nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 6
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50024204
(MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...)
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Affinity Data
Ki: 1.72E+3nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 2.85E+3nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM7966
([3H]histamine | 2-(1H-imidazol-4-yl)ethan-1-amine ...)
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Affinity Data
Ki: >1.00E+4nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM84342
(EPINEPHRINE | 4-[1-hydroxy-2-(methylamino)ethyl]be...)
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Affinity Data
Ki: >1.00E+4nM
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Date in BDB:
1/2/2012
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
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Affinity Data
Ki: >1.00E+4nM
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Date in BDB:
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM35234
(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
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Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/2/2012
Entry Details
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PubMed
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Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50019443
(LB-46 | 1-(1H-Indol-4-yloxy)-3-isopropylamino-prop...)
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Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/2/2012
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
5-hydroxytryptamine receptor 4
(Mouse)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50024210
(1H-indole-3-ethanamine | CHEMBL6640 | 2-(3-indolyl...)
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Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/2/2012
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
5-hydroxytryptamine receptor 7
(Human)
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM50000492
(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
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Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
1/2/2012
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL