Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50005929
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042653(7-[3-Bromo-4,5-bis-(4-fluoro-phenyl)-2-isopropyl-p...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042654(7-[3-(3-Bromo-phenyl)-2-(4-fluoro-phenyl)-5-isopro...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042656(7-[2,3-Bis-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042646(7-[3-(3-Chloro-phenyl)-2-(4-fluoro-phenyl)-5-isopr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042650(7-[2-(4-Fluoro-phenyl)-5-isopropyl-3-phenyl-pyrrol...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042652(7-[2-(4-Fluoro-phenyl)-5-isopropyl-3-pyridin-2-yl-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50004774(2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrah...)
Affinity DataIC50: 3nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50006412(Pravastatin | Eptastatin Sodium | (3R,5R)-3,5-dihy...)
Affinity DataIC50: 5nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042647(7-[2-(4-Fluoro-phenyl)-5-isopropyl-3-pyridin-4-yl-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042645(7-[3-(4-Fluoro-phenyl)-5-isopropyl-2-phenyl-pyrrol...)
Affinity DataIC50: 25nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042649(7-[2-(3-Bromo-phenyl)-3-(4-fluoro-phenyl)-5-isopro...)
Affinity DataIC50: 69nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042651(7-[2-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-5-isopr...)
Affinity DataIC50: 71nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50042655(7-[2,3-Bis-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-...)
Affinity DataIC50: 105nMAssay Description:Inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed