Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50036140
TargetCholecystokinin receptor type A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005463(1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-phen...)
Affinity DataIC50: 0.0800nMAssay Description:Antagonistic activity against cholecystokinin type A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetType-1 angiotensin II receptor(Rabbit)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009718(CHEMBL7550 | 2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetraz...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetRenin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044231(2-Benzyl-N-(4-cyclohexylmethyl-3-hydroxy-13-morpho...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50367879(LISINOPRIL)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM81962(S-L-365,260)
Affinity DataIC50: 2nMAssay Description:Antagonistic activity against cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044226(1-hydroxy-1-phenylethyl-phosphinoylamino]-propiony...)
Affinity DataIC50: 7nMAssay Description:Inhibition of metallopeptidase thermolysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50006842(CHEMBL37312 | 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-...)
Affinity DataIC50: 81nMAssay Description:Antagonistic activity against cholecystokinin type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50121926(1-[2-(1-Carboxy-ethylamino)-propionyl]-pyrrolidine...)
Affinity DataIC50: 90nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50019777(7-(9-Hydroxy-2-isobutyl-3-oxo-2,3,9,9a-tetrahydro-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonistic activity against cholecystokinin type A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044234(CHEMBL358439 | 1-[2-(1-Carboxy-ethylamino)-propion...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044230(1-(4-Carboxy-2-methyl-butyryl)-pyrrolidine-2-carbo...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044232(1-(3-Hydroxycarbamoyl-propionyl)-pyrrolidine-2-car...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50044233(1-(4-Carboxy-pentanoyl)-pyrrolidine-2-carboxylic a...)
Affinity DataIC50: 2.60E+5nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed