Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50006148
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000040(CHEMBL16192 | (+)(2-Benzhydryl-1-aza-bicyclo[2.2.2...)
Affinity DataIC50: 0.200nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21016([3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acet...)
Affinity DataIC50: 1.60nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030133((S)-2-Acetylamino-3-(1H-indol-3-yl)-propionic acid...)
Affinity DataIC50: 67nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030140([(S)-1-(3,5-Dimethyl-benzyloxycarbonyl)-2-(1H-indo...)
Affinity DataIC50: 125nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030130(2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propi...)
Affinity DataIC50: 133nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030138(2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propi...)
Affinity DataIC50: 280nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030139(2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propi...)
Affinity DataIC50: 413nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030117((S)-2-Dimethylamino-3-(1H-indol-3-yl)-propionic ac...)
Affinity DataIC50: 553nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030134((S)-2-Amino-3-(1H-indol-3-yl)-propionic acid 3,5-d...)
Affinity DataIC50: 1.53E+3nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030118(2-Ethylamino-3-(1H-indol-3-yl)-propionic acid benz...)
Affinity DataIC50: 3.80E+3nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50030124(2-Amino-3-(1H-indol-3-yl)-propionic acid benzyl es...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed