Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50006226
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046326(2-(3-Amino-2-oxo-4-phenyl-butyrylamino)-4-methyl-p...)
Affinity DataIC50: 500nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against aminopeptidase MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046329(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataIC50: 600nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046321(3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...)
Affinity DataIC50: 800nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046319(3-[2-Amino-3-(4-benzyloxy-phenyl)-propionyl]-benzo...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046315(2-Amino-3-(4-benzyloxy-phenyl)-1-(4-trifluoromethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046340(3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046325(2-(3-Amino-2-hydroxy-4-phenyl-butyrylamino)-4-meth...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046320(3-Amino-2-hydroxy-4-phenyl-butyric acid benzyl est...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046335(6-Amino-5-oxo-7-phenyl-heptanoic acid | CHEMBL3077...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046329(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against cytosolic leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against cytosolic leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046321(3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibitory concentration against cytosolic leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046329(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibitory concentration against aminopeptidase MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046337(3-((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyrylamino...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046330(3-Amino-2-oxo-4-phenyl-butyric acid methyl ester |...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046333(3-((2S,3R)-3-Amino-2-hydroxy-4-phenyl-butyrylamino...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022747(CHEMBL68979 | CHEMBL304141 | 2-(3-Amino-2-hydroxy-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046334(2-(3-Amino-2-hydroxy-4-phenyl-thiobutyrylamino)-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046314(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against cytosolic leucine aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046314(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against aminopeptidase MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeucyl-cystinyl aminopeptidase(Rat)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046321(3-Amino-4-(4-benzyloxy-phenyl)-2-hydroxy-butyric a...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against aminopeptidase MMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046328(3-Amino-N-benzyl-2-hydroxy-4-phenyl-butyramide | C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046324(2-(3-Amino-2-hydroxy-4-phenyl-thiobutyrylamino)-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046318({[(1-amino-2-phenylethyl)(hydroxy)phosphoryl]amino...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046313(3-Amino-1,4-diphenyl-butan-2-ol | CHEMBL69297)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046323(3-Amino-2-mercapto-4-phenyl-butyric acid methyl es...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046317(2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046322(3-Amino-2-hydroxy-4-phenyl-butyric acid methyl est...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046332((E)-3,3-Difluoro-4-oxo-6-phenyl-hex-5-enoic acid e...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046339((2S,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid | ...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046338(3,3-Difluoro-4-(5-methyl-1H-imidazol-4-yl)-4-oxo-b...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataKi:  18nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046314(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataKi:  46nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046316(2-Amino-3-(4-benzyloxy-phenyl)-propane-1-thiol | C...)
Affinity DataKi:  100nMAssay Description:Inhibition constant was determined against epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046314(3-Amino-4-(4-benzyloxy-phenyl)-2-oxo-butyric acid ...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition constant was determined against epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046327(3-Amino-1,4-diphenyl-butan-2-one | CHEMBL70658)
Affinity DataKi:  1.40E+4nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50046331(((2S,3S)-3-Amino-2-hydroxy-4-phenyl-butyrylamino)-...)
Affinity DataKi:  1.50E+4nMAssay Description:Ability to inhibit amidase activity of LTA4 hydrolase (1.4 ug) purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50279808(3-Amino-2-hydroxy-4-phenyl-butyric acid methyl est...)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of amidase activity of LTA4 hydrolase purified from human leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed