Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50006312
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047468(Pyridin-3-ylmethyl-(3,7,11-trimethyl-dodeca-2,6,10...)
Affinity DataIC50: 4nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)
Affinity DataIC50: 10nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047468(Pyridin-3-ylmethyl-(3,7,11-trimethyl-dodeca-2,6,10...)
Affinity DataIC50: 50nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047461(Benzyl-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-tri...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against squalene synthetase in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047470(Pyridin-4-ylmethyl-(3,7,11-trimethyl-dodeca-2,6,10...)
Affinity DataIC50: 100nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047464(Ethyl-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-ami...)
Affinity DataIC50: 600nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047459((3,7,11-Trimethyl-dodeca-2,6,10-trienyl)-(2,6,10-t...)
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047458(Ethyl-pyridin-3-ylmethyl-(3,7,11-trimethyl-dodeca-...)
Affinity DataIC50: 4.90E+3nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047460(Pyridin-3-ylmethyl-(3,7,11-trimethyl-dodecyl)-amin...)
Affinity DataIC50: 7.00E+3nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047463((3,7-Dimethyl-octa-2,6-dienyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 2.30E+4nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047462(Pyridin-3-ylmethyl-(2,6,10-trimethyl-undeca-5,9-di...)
Affinity DataIC50: 2.30E+4nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047469(3-(3,7,11-Trimethyl-dodeca-2,6,10-trienyloxymethyl...)
Affinity DataIC50: 3.30E+4nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047467(Bis-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-amine...)
Affinity DataIC50: 4.80E+4nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047465(Ethyl-bis-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)...)
Affinity DataIC50: 1.82E+5nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Rat)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50047466(3,7,11-Trimethyl-1-(3,7,11-trimethyl-dodeca-2,6,10...)
Affinity DataIC50: 8.28E+5nMAssay Description:Tested for inhibitory activity against squalene synthetase in the presence of inorganic pyrophosphate (PPi)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed