Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50006428
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048999(N-Hydroxy-N-methyl-3-(11-oxo-6,11-dihydro-dibenzo[...)
Affinity DataIC50: 10nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048989(3-(6,11-Dihydro-dibenzo[b,e]oxepin-2-yl)-N-hydroxy...)
Affinity DataIC50: 20nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 120nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048997(2-[2-(Hydroxy-isopropyl-amino)-ethyl]-6H-dibenzo[b...)
Affinity DataIC50: 130nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048998(N-Ethyl-N-hydroxy-3-(11-oxo-6,11-dihydro-dibenzo[b...)
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048990(N-Hydroxy-N-[2-(11-oxo-6,11-dihydro-dibenzo[b,e]ox...)
Affinity DataIC50: 190nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049003(N-Hydroxy-N-(11-oxo-6,11-dihydro-dibenzo[b,e]oxepi...)
Affinity DataIC50: 210nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048992(2-[2-(Hydroxy-methyl-amino)-ethyl]-6H-dibenzo[b,e]...)
Affinity DataIC50: 240nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048991(N-[2-(6,11-Dihydro-dibenzo[b,e]oxepin-2-yl)-ethyl]...)
Affinity DataIC50: 320nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049008(2-[2-(Ethyl-hydroxy-amino)-ethyl]-6,11-dihydro-dib...)
Affinity DataIC50: 450nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048994(2-[2-(Ethyl-hydroxy-amino)-ethyl]-6H-dibenzo[b,e]o...)
Affinity DataIC50: 480nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50006817(CHEMBL85776 | 9-Phenyl-nonanoic acid hydroxyamide ...)
Affinity DataIC50: 480nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048996(N-Ethyl-N-hydroxy-2-(11-oxo-6,11-dihydro-dibenzo[b...)
Affinity DataIC50: 580nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049006(N-Hydroxy-N-isopropyl-3-(11-oxo-6,11-dihydro-diben...)
Affinity DataIC50: 580nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049007(2-[3-(Hydroxy-methyl-amino)-propyl]-6H-dibenzo[b,e...)
Affinity DataIC50: 620nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049000(N-Hydroxy-2,2,N-trimethyl-3-(11-oxo-6,11-dihydro-d...)
Affinity DataIC50: 660nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049001(N-Cyclohexyl-N-hydroxy-2-(11-oxo-6,11-dihydro-dibe...)
Affinity DataIC50: 670nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50407748(CHEMBL2114190)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049002(N-Hydroxy-N-isopropyl-2-(11-oxo-6,11-dihydro-diben...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048995(N-Hydroxy-N-methyl-2-(11-oxo-6,11-dihydro-dibenzo[...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50049005(N-Cyclohexyl-N-hydroxy-3-(11-oxo-6,11-dihydro-dibe...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048988(N-Hydroxy-2-(11-oxo-6,11-dihydro-dibenzo[b,e]oxepi...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50048993(N-Methoxy-N-methyl-3-(11-oxo-6,11-dihydro-dibenzo[...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase by measuring 5-HETE levels in RBL-1 cell-free supernatantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed