Compile Data Set for Download or QSAR
Report error Found 147 Enz. Inhib. hit(s) with all data for entry = 50006475
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18224BDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049575BDBM50049575(1-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmeth...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049609BDBM50049609(6-{[(3,4-Dimethoxy-phenyl)-methyl-amino]-methyl}-p...)
Affinity DataIC50: 2.70nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18268BDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031867BDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049587BDBM50049587(1-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmeth...)
Affinity DataIC50: 5.10nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049583BDBM50049583(6-[(Methyl-naphthalen-2-yl-amino)-methyl]-pyrido[3...)
Affinity DataIC50: 7.20nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049604BDBM50049604(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-pyrido[3...)
Affinity DataIC50: 7.30nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049585BDBM50049585(1-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmeth...)
Affinity DataIC50: 7.5nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049611BDBM50049611(6-[(Methyl-phenyl-amino)-methyl]-pyrido[3,2-d]pyri...)
Affinity DataIC50: 8.40nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049609BDBM50049609(6-{[(3,4-Dimethoxy-phenyl)-methyl-amino]-methyl}-p...)
Affinity DataIC50: 9.80nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18268BDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049603BDBM50049603(6-{[(2,4-Dimethoxy-phenyl)-methyl-amino]-methyl}-p...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049587BDBM50049587(1-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmeth...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049607BDBM50049607(6-{[(3-Methoxy-phenyl)-methyl-amino]-methyl}-pyrid...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049576BDBM50049576(6-{[(2-Chloro-phenyl)-methyl-amino]-methyl}-pyrido...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049599BDBM50049599(1-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmeth...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049603BDBM50049603(6-{[(2,4-Dimethoxy-phenyl)-methyl-amino]-methyl}-p...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049601BDBM50049601(6-{[(4-Methoxy-phenyl)-methyl-amino]-methyl}-pyrid...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049583BDBM50049583(6-[(Methyl-naphthalen-2-yl-amino)-methyl]-pyrido[3...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18224BDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031869BDBM50031869(6-{[(4,5-Dichloro-phenyl)-methyl-amino]-methyl}-py...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049604BDBM50049604(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-pyrido[3...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049601BDBM50049601(6-{[(4-Methoxy-phenyl)-methyl-amino]-methyl}-pyrid...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031866BDBM50031866(6-(((3-chlorophenyl)(methyl)amino)methyl)pyrido[3,...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049599BDBM50049599(1-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmeth...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049611BDBM50049611(6-[(Methyl-phenyl-amino)-methyl]-pyrido[3,2-d]pyri...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049579BDBM50049579(6-{[(2,5-Dichloro-phenyl)-methyl-amino]-methyl}-py...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049613BDBM50049613(6-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-p...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049582BDBM50049582(6-(Naphthalen-1-ylaminomethyl)-pyrido[3,2-d]pyrimi...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031867BDBM50031867(6-((methyl(3,4,5-trimethoxyphenyl)amino)methyl)pyr...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049612BDBM50049612(6-{[(2-Methoxy-phenyl)-methyl-amino]-methyl}-pyrid...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049575BDBM50049575(1-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmeth...)
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031869BDBM50031869(6-{[(4,5-Dichloro-phenyl)-methyl-amino]-methyl}-py...)
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049608BDBM50049608(6-[(2,6-Dichloro-phenylamino)-methyl]-pyrido[3,2-d...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049586BDBM50049586(6-{[(2,6-Dichloro-phenyl)-methyl-amino]-methyl}-py...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Baker's yeast)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18224BDBM18224(6-[(2,5-dimethoxyphenyl)methyl]-5-methylpyrido[2,3...)
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049590BDBM50049590(1-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmeth...)
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049607BDBM50049607(6-{[(3-Methoxy-phenyl)-methyl-amino]-methyl}-pyrid...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Baker's yeast)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031869BDBM50031869(6-{[(4,5-Dichloro-phenyl)-methyl-amino]-methyl}-py...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049588BDBM50049588(6-{[Methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049582BDBM50049582(6-(Naphthalen-1-ylaminomethyl)-pyrido[3,2-d]pyrimi...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031868BDBM50031868(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-pyrido[3...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Baker's yeast)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049604BDBM50049604(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-pyrido[3...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Baker's yeast)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18268BDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049591BDBM50049591(6-{[Methyl-(2,4,6-trichloro-phenyl)-amino]-methyl}...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049589BDBM50049589(6-[(3,4,5-Trichloro-phenylamino)-methyl]-pyrido[3,...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049590BDBM50049590(1-{4-[(2,4-Diamino-pyrido[3,2-d]pyrimidin-6-ylmeth...)
Affinity DataIC50: 46nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049615BDBM50049615(6-[(2,4,6-Trichloro-phenylamino)-methyl]-pyrido[3,...)
Affinity DataIC50: 46nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049579BDBM50049579(6-{[(2,5-Dichloro-phenyl)-methyl-amino]-methyl}-py...)
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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