Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50006477
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049682(2-Methoxy-6-(5-methyl-[1,3,4]oxadiazol-2-yl)-10,10...)
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049686(2-Methoxy-6-(2-methyl-2H-tetrazol-5-yl)-10,10-diox...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049703(6-(2-Methyl-2H-tetrazol-5-yl)-10,10-dioxo-2-propox...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049704(2-(5-Methyl-[1,3,4]oxadiazol-2-yl)-10,11-dioxa-dib...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against Monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049666(5-(10,10-Dioxo-10H-10lambda*6*-phenoxathiin-2-yl)-...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049701(3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-10,10-dioxo-10H...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049671(2-Methyl-6-(5-methyl-[1,3,4]oxadiazol-2-yl)-10,10-...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049687(2-Isopropyl-6-(2-methyl-2H-tetrazol-5-yl)-10,10-di...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049680(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-ethoxy-10,10-di...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049668(6-(4,5-Dihydro-1H-imidazol-2-yl)-10,10-dioxo-2-pro...)
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against rat brain mitochondrial Monoamine oxidase A (Expt 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049665(2-Allylamino-6-(4,5-dihydro-1H-imidazol-2-yl)-10,1...)
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049679(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-ethyl-10,10-dio...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049677(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-morpholin-4-yl-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049698(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-methoxy-10,10-d...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049699(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-ethylamino-10,1...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049688(3-(2-Methyl-2H-tetrazol-5-yl)-10,10-dioxo-10H-10la...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049675(6-(4,5-Dihydro-1H-imidazol-2-yl)-10,10-dioxo-2-pro...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049706(6-(4,5-Dihydro-1H-imidazol-2-yl)-10,10-dioxo-2-thi...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049705(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-dimethylamino-1...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049689(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-methyl-10,10-di...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049683(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-methylamino-10,...)
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049685(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-(ethyl-methyl-a...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049670(6-(4,5-Dihydro-1H-imidazol-2-yl)-10,10-dioxo-2-pro...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049690(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-(2-hydroxy-ethy...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049668(6-(4,5-Dihydro-1H-imidazol-2-yl)-10,10-dioxo-2-pro...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against rat brain mitochondrial Monoamine oxidase A (Expt 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049691(2-(10,10-Dioxo-10H-10lambda*6*-phenoxathiin-2-yl)-...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049693(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-isopropyl-10,10...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049678(6-(5-Methyl-[1,3,4]oxadiazol-2-yl)-2-propoxy-thiox...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049686(2-Methoxy-6-(2-methyl-2H-tetrazol-5-yl)-10,10-diox...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against rat brain mitochondrial Monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049684(2-Chloro-6-(4,5-dihydro-1H-imidazol-2-yl)-10,10-di...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049674(3-(5-Methoxy-[1,3,4]oxadiazol-2-yl)-10,10-dioxo-10...)
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049702(3-(5-Methoxy-[1,2,4]oxadiazol-3-yl)-10,10-dioxo-10...)
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049692(2-Phenoxathiin-2-yl-4,5-dihydro-1H-imidazole | CHE...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049682(2-Methoxy-6-(5-methyl-[1,3,4]oxadiazol-2-yl)-10,10...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against rat brain mitochondrial Monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049672(6-(2-Ethyl-2H-tetrazol-5-yl)-2-hydroxy-xanthen-9-o...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against rat brain mitochondrial Monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049696(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-fluoro-10,10-di...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049697(5-Methyl-3-phenoxathiin-2-yl-[1,2,4]oxadiazole | C...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049681(2-(2-Amino-ethylamino)-6-(4,5-dihydro-1H-imidazol-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049700(2-Thianthren-2-yl-4,5-dihydro-1H-imidazole | CHEMB...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against Monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049694(3-(4,5-Dihydro-1H-imidazol-2-yl)-10,10-dioxo-10H-1...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049667(3-(5-Ethyl-[1,3,4]oxadiazol-2-yl)-10,10-dioxo-10H-...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049695(2-tert-Butyl-6-(4,5-dihydro-1H-imidazol-2-yl)-10,1...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049673(2-[8-(4,5-dihydro-1H-2-imidazolyl)-2-phenoxathiiny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049678(6-(5-Methyl-[1,3,4]oxadiazol-2-yl)-2-propoxy-thiox...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against rat brain mitochondrial Monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049676(3-(4,5-Dihydro-1H-imidazol-2-yl)-thioxanthen-9-one...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049672(6-(2-Ethyl-2H-tetrazol-5-yl)-2-hydroxy-xanthen-9-o...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against rat brain mitochondrial monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049669(2-(10,10-Dioxo-10H-10lambda*6*-2-[8-(4,5-dihydro-1...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against rat brain mitochondrial Monoamine oxidase B 0.1(uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049673(2-[8-(4,5-dihydro-1H-2-imidazolyl)-2-phenoxathiiny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat brain mitochondrial Monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049692(2-Phenoxathiin-2-yl-4,5-dihydro-1H-imidazole | CHE...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against rat brain mitochondrial Monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049679(6-(4,5-Dihydro-1H-imidazol-2-yl)-2-ethyl-10,10-dio...)
Affinity DataKi:  4nMAssay Description:Ex vivo value for inhibition of MAO A of rats sacrificed 2 hr after po administrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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