Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50006529
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  0.900nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050482(10-Amino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  2.29nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050482(10-Amino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  2.30nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050482(10-Amino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  6.62nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050479(3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15...)
Affinity DataKi:  17nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050487(10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  25.2nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050487(10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  25.2nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050479(3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15...)
Affinity DataKi:  27.7nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  40.6nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  41nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050481(10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3...)
Affinity DataKi:  52nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050481(10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3...)
Affinity DataKi:  91.6nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050485((1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricy...)
Affinity DataKi:  102nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  109nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050487(10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  123nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  132nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050483(9,13-dimethyl-13-azatetracyclo[7.5.1.01,12.03,8]pe...)
Affinity DataKi:  179nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050483(9,13-dimethyl-13-azatetracyclo[7.5.1.01,12.03,8]pe...)
Affinity DataKi:  215nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050478(10-Dimethylamino-1,9-dimethyl-tricyclo[7.3.1.0*2,7...)
Affinity DataKi:  297nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050478(10-Dimethylamino-1,9-dimethyl-tricyclo[7.3.1.0*2,7...)
Affinity DataKi:  297nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataKi:  330nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050480(9-Hydroxymethyl-1-methyl-10-methylamino-tricyclo[7...)
Affinity DataKi:  380nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050480(9-Hydroxymethyl-1-methyl-10-methylamino-tricyclo[7...)
Affinity DataKi:  380nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050478(10-Dimethylamino-1,9-dimethyl-tricyclo[7.3.1.0*2,7...)
Affinity DataKi:  409nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050481(10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3...)
Affinity DataKi:  459nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050482(10-Amino-9-methoxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi:  467nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050480(9-Hydroxymethyl-1-methyl-10-methylamino-tricyclo[7...)
Affinity DataKi:  650nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050485((1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricy...)
Affinity DataKi:  795nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050477(10-Dimethylamino-9-hydroxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  830nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050477(10-Dimethylamino-9-hydroxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  830nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050479(3,9-dimethyl-3,5-diazatetracyclo[7.7.1.01,6.010,15...)
Affinity DataKi:  863nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050487(10-Dimethylamino-9-methoxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  1.40E+3nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050477(10-Dimethylamino-9-hydroxymethyl-1-methyl-tricyclo...)
Affinity DataKi:  2.90E+3nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Bovine)
Institute

Curated by ChEMBL
LigandPNGBDBM50050486(1-methoxymethyl-9-methyl-(1S,9R)-2,3,4,5-tetraazat...)
Affinity DataKi:  3.80E+3nMAssay Description:Activity was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050485((1R,9R)-9-Methoxymethyl-1,10-dimethyl-10-aza-tricy...)
Affinity DataKi: >5.00E+3nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Institute

Curated by ChEMBL
LigandPNGBDBM50050486(1-methoxymethyl-9-methyl-(1S,9R)-2,3,4,5-tetraazat...)
Affinity DataKi: >1.00E+4nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]U-69593 at Opioid receptor kappa 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050483(9,13-dimethyl-13-azatetracyclo[7.5.1.01,12.03,8]pe...)
Affinity DataKi: >1.00E+4nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050478(10-Dimethylamino-1,9-dimethyl-tricyclo[7.3.1.0*2,7...)
Affinity DataKi:  1.00E+4nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050486(1-methoxymethyl-9-methyl-(1S,9R)-2,3,4,5-tetraazat...)
Affinity DataKi: >1.00E+4nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050480(9-Hydroxymethyl-1-methyl-10-methylamino-tricyclo[7...)
Affinity DataKi: >1.00E+6nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050477(10-Dimethylamino-9-hydroxymethyl-1-methyl-tricyclo...)
Affinity DataKi: >1.00E+6nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50050484(10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...)
Affinity DataKi: >1.00E+6nMAssay Description:Activity was evaluated by inhibition of the binding of 1 nM [3H]DPDPE at Opioid receptor delta 1 binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed