Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 320
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM499(CHEMBL64802 | Cancer Chemotherapy National Service...)
Affinity DataIC50: 320nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM502(2-({4-[bis(3-hydroxy-1,4-dioxo-1,4-dihydronaphthal...)
Affinity DataIC50: 750nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM506(3-({4-[bis(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]...)
Affinity DataIC50: 1.70E+3nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM510(11,12-dihydroxy-5,10-dioxo-4a,5,10,11,12,12a-hexah...)
Affinity DataIC50: 2.00E+3nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM503(CHEMBL64588 | Cancer Chemotherapy National Service...)
Affinity DataIC50: 6.00E+3nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM514(Cancer Chemotherapy National Service Center (CCNSC...)
Affinity DataIC50: 1.30E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM507(Cancer Chemotherapy National Service Center (CCNSC...)
Affinity DataIC50: 1.60E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM511(Cancer Chemotherapy National Service Center (CCNSC...)
Affinity DataIC50: 1.70E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM500(Cancer Chemotherapy National Service Center (CCNSC...)
Affinity DataIC50: 2.10E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM504(2-acetamido-2-(thiophen-3-ylmethyl)propanedioic ac...)
Affinity DataIC50: 2.30E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM508(2-[(2,4-dichlorophenyl)(3-hydroxy-1,4-dioxo-1,4-di...)
Affinity DataIC50: 2.40E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM512(2-butanoyl-6-[(3-butanoyl-2,4,6-trihydroxy-5-methy...)
Affinity DataIC50: 2.60E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM501(Cancer Chemotherapy National Service Center (CCNSC...)
Affinity DataIC50: 2.70E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM505(Cancer Chemotherapy National Service Center (CCNSC...)
Affinity DataIC50: 3.00E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM516(N-[2,6-bis(propan-2-yl)phenyl]-6-(4-hydroxy-2-oxo-...)
Affinity DataIC50: 3.10E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM509(phenyl N-(2-hydroxy-1,2-diphenylethyl)-N-(2-hydrox...)
Affinity DataIC50: 3.20E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM513((2S,3R,4R,4aS,6aR,6bR,8aS,12aS,14aS,14bR)-2,3-dihy...)
Affinity DataIC50: 3.50E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
National Institutes of Health

LigandPNGBDBM515(Cancer Chemotherapy National Service Center (CCNSC...)
Affinity DataIC50: 4.20E+4nMpH: 6.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2004
Entry Details Article
PubMed