Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50003432
LigandPNGBDBM50036910(4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole | CHEMBL3...)
Affinity DataKi:  13nMAssay Description:Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain using 0.2 nM [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50036913(4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole | med...)
Affinity DataKi:  25nMAssay Description:Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50470860(CHEMBL105328)
Affinity DataKi:  33nMAssay Description:Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain using 0.2 nM [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50470860(CHEMBL105328)
Affinity DataKi:  55nMAssay Description:Alpha-1 adrenergic receptor binding affinity in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50470861(CHEMBL322844)
Affinity DataKi:  57nMAssay Description:Alpha-1 adrenergic receptor binding affinity in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50470859(CHEMBL105487)
Affinity DataKi:  122nMAssay Description:Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain using 0.2 nM [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50036910(4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole | CHEMBL3...)
Affinity DataEC50:  153nMAssay Description:50% Molar effective concentration for agonistic activity against Alpha-1 adrenergic receptor in rat aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50470860(CHEMBL105328)
Affinity DataEC50:  156nMAssay Description:50% Molar effective concentration for agonistic activity against Alpha-1 adrenergic receptor in rat aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50470862(CHEMBL102076)
Affinity DataKi:  165nMAssay Description:Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain using 0.2 nM [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50223426(CHEBI:10304 | Corbadrine | Levonordefrin | Neo-Cob...)
Affinity DataKi:  205nMAssay Description:Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50036910(4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole | CHEMBL3...)
Affinity DataKi:  224nMAssay Description:Alpha-1 adrenergic receptor binding affinity in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50036913(4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole | med...)
Affinity DataEC50:  281nMAssay Description:50% Molar effective concentration afainst Alpha-1 adrenergic receptor in rat aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50470863(CHEMBL102669)
Affinity DataKi:  387nMAssay Description:Alpha-1 adrenergic receptor binding affinity in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50470862(CHEMBL102076)
Affinity DataKi:  574nMAssay Description:Alpha-1 adrenergic receptor binding affinity in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50470864(CHEMBL420652)
Affinity DataKi:  655nMAssay Description:Alpha-1 adrenergic receptor binding affinity in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50036913(4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole | med...)
Affinity DataKi:  1.11E+3nMAssay Description:Alpha-1 adrenergic receptor binding affinity in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50470864(CHEMBL420652)
Affinity DataKi:  1.45E+3nMAssay Description:Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50470863(CHEMBL102669)
Affinity DataKi:  1.47E+3nMAssay Description:Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain using 0.2 nM [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50470859(CHEMBL105487)
Affinity DataKi:  1.73E+3nMAssay Description:Alpha-1 adrenergic receptor binding affinity in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50470861(CHEMBL322844)
Affinity DataKi:  1.89E+3nMAssay Description:Alpha-2 adrenergic receptor binding affinity was tested against membrane preparations of rat brain using 0.2 nM [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50036913(4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole | med...)
Affinity DataIC50: 2.90E+3nMAssay Description:Alpha-2 adrenergic receptor antagonistic activity in human blood platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50036910(4-(1-Naphthalen-1-yl-ethyl)-1H-imidazole | CHEMBL3...)
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonistic activity against Alpha-2 adrenergic receptor in human blood plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50223426(CHEBI:10304 | Corbadrine | Levonordefrin | Neo-Cob...)
Affinity DataKi:  9.22E+3nMAssay Description:Alpha-1 adrenergic receptor binding affinity in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50470860(CHEMBL105328)
Affinity DataIC50: 1.43E+4nMAssay Description:Alpha-2 adrenergic receptor antagonistic activity in human blood platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50470864(CHEMBL420652)
Affinity DataIC50: 9.77E+4nMAssay Description:Alpha-2 adrenergic receptor antagonistic activity in human blood platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Ohio State University

Curated by ChEMBL
LigandPNGBDBM50470861(CHEMBL322844)
Affinity DataIC50: 2.15E+5nMAssay Description:Alpha-2 adrenergic receptor antagonistic activity in human blood platelets.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed