Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50006837
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataIC50: 0.670nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054484(CVS-1778 | N-((S)-1-Formyl-4-guanidino-butyl)-2-((...)
Affinity DataIC50: 0.710nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054482((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...)
Affinity DataIC50: 1.20nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054482((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...)
Affinity DataIC50: 1.20nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50: 1.70nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50: 1.70nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 1.80nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 1.80nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-...)
Affinity DataIC50: 12.4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054484(CVS-1778 | N-((S)-1-Formyl-4-guanidino-butyl)-2-((...)
Affinity DataIC50: 20.6nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054485(N-[(S)-1-((R)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataIC50: 28.8nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50: 113nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50: 113nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054482((S)-4-[(S)-2-((S)-1-Formyl-4-guanidino-butylcarbam...)
Affinity DataIC50: 301nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054484(CVS-1778 | N-((S)-1-Formyl-4-guanidino-butyl)-2-((...)
Affinity DataIC50: 329nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-...)
Affinity DataIC50: 1.55E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054483((S)-4-{(S)-2-[(S)-1-(1-Carbamimidoyl-piperidin-3-y...)
Affinity DataIC50: 2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 1.51E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054487(N-[(S)-1-(1-Carbamimidoyl-piperidin-3-ylmethyl)-2-...)
Affinity DataIC50: 1.51E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054485(N-[(S)-1-((R)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054485(N-[(S)-1-((R)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataIC50: 6.07E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054486(N-[(S)-1-((S)-1-Carbamimidoyl-piperidin-3-ylmethyl...)
Affinity DataIC50: 6.48E+4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed