Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50003441
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50027970(Brodimoprim | 5-(4-Bromo-3,5-dimethoxy-benzyl)-pyr...)
Affinity DataIC50: 3nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 5.90nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50404462(4-Hydroxytrimethoprim | CHEMBL1181)
Affinity DataIC50: 11nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50405965(CHEMBL287241)
Affinity DataIC50: 18nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50405982(CHEMBL56602)
Affinity DataIC50: 35nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50138701(6-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,...)
Affinity DataIC50: 100nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50404463(CHEMBL339058)
Affinity DataIC50: 302nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50081908(5-(3-Methoxy-benzyl)-pyrimidine-2,4-diamine | CHEM...)
Affinity DataIC50: 398nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50405966(CHEMBL56101)
Affinity DataIC50: 398nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50470948(CHEMBL347759)
Affinity DataIC50: 501nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50406000(CHEMBL19293)
Affinity DataIC50: 501nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50405973(CHEMBL417095)
Affinity DataIC50: 724nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50405980(CHEMBL31619)
Affinity DataIC50: 1.48E+3nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataIC50: 1.95E+3nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50470947(CHEMBL144153)
Affinity DataIC50: 2.51E+3nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50470946(Alpha-Hydroxytrimethoprim)
Affinity DataIC50: 4.47E+3nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50470946(Alpha-Hydroxytrimethoprim)
Affinity DataIC50: 4.47E+3nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50188083(5-[1-(3,4,5-Trimethoxy-phenyl)-ethyl]-pyrimidine-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50188083(5-[1-(3,4,5-Trimethoxy-phenyl)-ethyl]-pyrimidine-2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50224283(CHEMBL283279)
Affinity DataIC50: 1.66E+6nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed