Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50006934
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055881(1-(4-Fluoro-benzyl)-4-[2-(phenyl-thiophen-2-yl-met...)
Affinity DataIC50: 13.8nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055870(1-(4-Fluoro-benzyl)-4-{2-[(4-fluoro-phenyl)-phenyl...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50049362(4-(2-Benzhydryloxy-ethyl)-1-benzyl-piperidine | CH...)
Affinity DataIC50: 15.2nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataIC50: 16.4nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 17.2nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055875(4-(2-Benzhydryloxy-ethyl)-1-(4-methyl-benzyl)-pipe...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055879(4-(2-Benzhydryloxy-ethyl)-1-(4-chloro-benzyl)-pipe...)
Affinity DataIC50: 24.7nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055873(1-Benzyl-4-[2-(phenyl-thiophen-2-yl-methoxy)-ethyl...)
Affinity DataIC50: 27.2nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055878(4-(2-Benzhydryloxy-ethyl)-1-(4-methoxy-benzyl)-pip...)
Affinity DataIC50: 27.8nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055880(4-(2-Benzhydryloxy-ethyl)-1-(3-chloro-4-fluoro-ben...)
Affinity DataIC50: 28.2nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataIC50: 31.1nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055869(TCMDC-136045 | 3-[4-(2-Benzhydryloxy-ethyl)-piperi...)
Affinity DataIC50: 48.6nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055877(4-{2-[(4-Chloro-phenyl)-phenyl-methoxy]-ethyl}-1-(...)
Affinity DataIC50: 52.4nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055866(3-{4-[2-(Phenyl-thiophen-2-yl-methoxy)-ethyl]-pipe...)
Affinity DataIC50: 58.3nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055867(4-(2-Benzhydryloxy-ethyl)-1-thiophen-2-ylmethyl-pi...)
Affinity DataIC50: 59.3nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 82nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055872(4-(2-Benzhydryloxy-ethyl)-1-(3,4-dichloro-benzyl)-...)
Affinity DataIC50: 85.7nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055868(4-[4-(2-Benzhydryloxy-ethyl)-piperidin-1-ylmethyl]...)
Affinity DataIC50: 101nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Organix

Curated by ChEMBL
LigandPNGBDBM50055874(4-(2-Benzhydryloxy-ethyl)-1-benzo[b]thiophen-2-ylm...)
Affinity DataIC50: 172nMAssay Description:In vitro inhibition of [3H]WIN-35 428 binding to dopamine transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055869(TCMDC-136045 | 3-[4-(2-Benzhydryloxy-ethyl)-piperi...)
Affinity DataIC50: 680nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055873(1-Benzyl-4-[2-(phenyl-thiophen-2-yl-methoxy)-ethyl...)
Affinity DataIC50: 741nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50049362(4-(2-Benzhydryloxy-ethyl)-1-benzyl-piperidine | CH...)
Affinity DataIC50: 743nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055866(3-{4-[2-(Phenyl-thiophen-2-yl-methoxy)-ethyl]-pipe...)
Affinity DataIC50: 927nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055878(4-(2-Benzhydryloxy-ethyl)-1-(4-methoxy-benzyl)-pip...)
Affinity DataIC50: 1.24E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055867(4-(2-Benzhydryloxy-ethyl)-1-thiophen-2-ylmethyl-pi...)
Affinity DataIC50: 1.25E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055870(1-(4-Fluoro-benzyl)-4-{2-[(4-fluoro-phenyl)-phenyl...)
Affinity DataIC50: 1.26E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055875(4-(2-Benzhydryloxy-ethyl)-1-(4-methyl-benzyl)-pipe...)
Affinity DataIC50: 1.39E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055881(1-(4-Fluoro-benzyl)-4-[2-(phenyl-thiophen-2-yl-met...)
Affinity DataIC50: 1.39E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055871(4-(2-Benzhydryloxy-ethyl)-1-(4-bromo-benzyl)-piper...)
Affinity DataIC50: 1.49E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055874(4-(2-Benzhydryloxy-ethyl)-1-benzo[b]thiophen-2-ylm...)
Affinity DataIC50: 1.54E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055868(4-[4-(2-Benzhydryloxy-ethyl)-piperidin-1-ylmethyl]...)
Affinity DataIC50: 1.57E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055879(4-(2-Benzhydryloxy-ethyl)-1-(4-chloro-benzyl)-pipe...)
Affinity DataIC50: 1.61E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055882(4-(2-Benzhydryloxy-ethyl)-1-(4-nitro-benzyl)-piper...)
Affinity DataIC50: 1.77E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055877(4-{2-[(4-Chloro-phenyl)-phenyl-methoxy]-ethyl}-1-(...)
Affinity DataIC50: 1.81E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50: 1.92E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055880(4-(2-Benzhydryloxy-ethyl)-1-(3-chloro-4-fluoro-ben...)
Affinity DataIC50: 2.53E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50055872(4-(2-Benzhydryloxy-ethyl)-1-(3,4-dichloro-benzyl)-...)
Affinity DataIC50: 2.88E+3nMAssay Description:In vitro inhibition of [3H]citalopram binding to serotonin transporter on rat striatal membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed