Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50006959
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50049756(A-84543 | 3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-...)
Affinity DataKi:  1.53E+3nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [125I]alpha-bungarotoxin from K-28 cells stably express human Nicotinic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  1.61E+3nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [125I]alpha-bungarotoxin from K-28 cells stably express human Nicotinic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50035398(ABT-418 | (S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-...)
Affinity DataKi:  4.05E+3nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [125I]alpha-bungarotoxin from K-28 cells stably express human Nicotinic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056147(ABT-089 | 2-Methyl-3-((S)-1-pyrrolidin-2-ylmethoxy...)
Affinity DataKi: >1.00E+4nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [125I]alpha-bungarotoxin from K-28 cells stably express human Nicotinic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056150(2-Methyl-3-((R)-1-pyrrolidin-2-ylmethoxy)-pyridine...)
Affinity DataKi: >1.00E+4nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [125I]alpha-bungarotoxin from K-28 cells stably express human Nicotinic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056149(2-Methyl-3-((R)-1-methyl-pyrrolidin-2-ylmethoxy)-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [125I]alpha-bungarotoxin from K-28 cells stably express human Nicotinic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056148(2-Methyl-3-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [125I]alpha-bungarotoxin from K-28 cells stably express human Nicotinic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed