Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50006994
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056588((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 2nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056588((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 2nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056589((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 3nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plate; 3:1 mixture enriched in the faster eluting diastereoisomerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056584((S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-...)
Affinity DataIC50: 5nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056586((S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-9-chloro-...)
Affinity DataIC50: 7nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056587(3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-2,5-...)
Affinity DataIC50: 11nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056589((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 12nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plate; 1:3 mixture enriched in the slower eluting diastereoisomerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056585((R)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 18nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056585((R)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 18nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056588((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 34nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056588((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 34nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056588((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 60nMAssay Description:Inhibition of thrombin-induced platelet aggregation assay at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056590((R)-3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-...)
Affinity DataIC50: 60nMAssay Description:Binding affinity for soluble GPIIb/IIIa captured on fibrinogen coated microtiter plateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056584((S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-...)
Affinity DataIC50: 78nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056589((S)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 92nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056587(3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-2,5-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056584((S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-...)
Affinity DataIC50: 138nMAssay Description:Inhibition of thrombin-induced platelet aggregation assay at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056586((S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-9-chloro-...)
Affinity DataIC50: 159nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056587(3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-2,5-...)
Affinity DataIC50: 213nMAssay Description:Inhibition of thrombin-induced platelet aggregation assay at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056586((S)-3-[7-(4-Carbamimidoyl-phenylethynyl)-9-chloro-...)
Affinity DataIC50: 313nMAssay Description:Inhibition of thrombin-induced platelet aggregation assay at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056590((R)-3-[7-(4-Carbamimidoyl-phenylethynyl)-1-methyl-...)
Affinity DataIC50: 820nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056585((R)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50056585((R)-3-[1-tert-Butyl-7-(4-carbamimidoyl-phenylethyn...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of 17.5 uM ADP-induced platelet aggregation of human platelet-rich plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed