Compile Data Set for Download or QSAR
Report error Found 85 Enz. Inhib. hit(s) with all data for entry = 50007081
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057877(4-[2-(4-Fluoro-phenyl)-pyrrol-1-yl]-benzenesulfona...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057886(3-Bromo-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-p...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057869(3-(4-Chloro-phenoxymethyl)-1-(4-fluoro-phenyl)-5-(...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057902(2-(4-Methanesulfonyl-phenyl)-5-methyl-1-p-tolyl-1H...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057888(3-Chloro-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057904(1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057906(2-(4-Methanesulfonyl-phenyl)-5-methyl-1-phenyl-1H-...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057903(1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057900(3-(3-Chloro-phenoxymethyl)-1-(4-fluoro-phenyl)-5-(...)
Affinity DataIC50: 80nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057899(2-(4-Methanesulfonyl-phenyl)-5-methyl-1-(4-trifluo...)
Affinity DataIC50: 80nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057882(2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057884(1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057892(1-(3,4-Difluoro-phenyl)-2-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057901(Acetic acid 1-(4-fluoro-phenyl)-5-(4-methanesulfon...)
Affinity DataIC50: 470nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057905(2-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50: 510nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057890(1-Cyclohexyl-2-(4-methanesulfonyl-phenyl)-5-methyl...)
Affinity DataIC50: 520nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057895(1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 750nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057886(3-Bromo-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-p...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057875(3-[1-(4-Acetyl-phenyl)-5-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 in retinoic acid stimulated HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057868([1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 1.02E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057883(2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50: 1.44E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057870(1-[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 1.61E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057875(3-[1-(4-Acetyl-phenyl)-5-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 in IL-1-stimulated dermal fibroblastsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057867(1-{4-[2-(4-Methanesulfonyl-phenyl)-5-methyl-pyrrol...)
Affinity DataIC50: 2.87E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057898(1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2...)
Affinity DataIC50: 3.23E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057891([1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 3.88E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057888(3-Chloro-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-...)
Affinity DataIC50: 4.50E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057875(3-[1-(4-Acetyl-phenyl)-5-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataIC50: 4.60E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057871(3-[1-(4-Dimethylsulfamoyl-phenyl)-5-(4-fluoro-phen...)
Affinity DataIC50: 7.50E+3nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057882(2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057894(1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-1...)
Affinity DataIC50: 1.02E+4nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057877(4-[2-(4-Fluoro-phenyl)-pyrrol-1-yl]-benzenesulfona...)
Affinity DataIC50: 1.05E+4nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057875(3-[1-(4-Acetyl-phenyl)-5-(4-methoxy-phenyl)-1H-pyr...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057868([1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057885(3-[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057887(4-[2-(4-Fluoro-phenyl)-pyrrol-1-yl]-N-methyl-benze...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057883(2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methan...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057881(1-(3-Chloro-4-methanesulfonyl-phenyl)-2-(4-fluoro-...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057878(2-(4-Methanesulfonyl-phenyl)-5-methyl-1H-pyrrole |...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057880(2-Ethyl-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057874(2-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057876([1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057872(1-(4-Ethanesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057873(1-Butyl-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057865(2-(4-Fluoro-phenyl)-1-(3-methanesulfonyl-phenyl)-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057866(1-Isopropyl-2-(4-methanesulfonyl-phenyl)-5-methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057893(1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057896(4-[2-(4-Fluoro-phenyl)-pyrrol-1-yl]-N,N-dimethyl-b...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057901(Acetic acid 1-(4-fluoro-phenyl)-5-(4-methanesulfon...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057879(1-(4-Fluoro-benzyl)-2-(4-methanesulfonyl-phenyl)-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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