Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50036520
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058237((S)-2-(Butane-1-sulfonylamino)-3-{[4-oxo-5-(2-pipe...)
Affinity DataKd:  1.40nMAssay Description:Displacement of L-736,622 from purified resting Fibrinogen ReceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058238(CHEMBL540024 | CHEMBL288521 | 3-{[4-Oxo-5-(2-piper...)
Affinity DataKd:  590nMAssay Description:Displacement of L-736,622 from purified resting Fibrinogen ReceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50033030(3-{2-[2-Oxo-3-(2-piperidin-4-yl-ethyl)-piperidin-1...)
Affinity DataKd:  600nMAssay Description:Displacement of L-736,622 from purified resting Fibrinogen ReceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058236((S)-2-(Butane-1-sulfonylamino)-3-{[4-oxo-5-(2-pipe...)
Affinity DataKd:  1.80nMAssay Description:Displacement of L-736,622 from purified resting Fibrinogen ReceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058240(3-{[4-Oxo-5-(2-piperidin-4-yl-ethyl)-5,6,7,8-tetra...)
Affinity DataKd:  680nMAssay Description:Displacement of L-736,622 from purified resting Fibrinogen ReceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058239((S)-3-{[4-Oxo-5-(2-piperidin-4-yl-ethyl)-5,6,7,8-t...)
Affinity DataKd:  1.10nMAssay Description:Displacement of L-736,622 from purified resting Fibrinogen ReceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058239((S)-3-{[4-Oxo-5-(2-piperidin-4-yl-ethyl)-5,6,7,8-t...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058239((S)-3-{[4-Oxo-5-(2-piperidin-4-yl-ethyl)-5,6,7,8-t...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to fibrinogen (FG)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50058239((S)-3-{[4-Oxo-5-(2-piperidin-4-yl-ethyl)-5,6,7,8-t...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human umbilical vein endothelial cells (HUVEC) attachment to vitronectin (VN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed