Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50007298
TargetAlpha-1A adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060964(5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]...)
Affinity DataKi:  0.0290nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1A adrenergic receptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060964(5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]...)
Affinity DataKi:  0.0580nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1D adrenergic receptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  0.220nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1A adrenergic receptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060964(5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]...)
Affinity DataKi:  0.610nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1B adrenergic receptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033111(6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...)
Affinity DataKi:  0.850nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1D adrenergic receptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  0.970nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1D adrenergic receptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033111(6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...)
Affinity DataKi:  2nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1A adrenergic receptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033111(6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...)
Affinity DataKi:  2.68nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1B adrenergic receptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060964(5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]...)
Affinity DataKi:  6.80nMAssay Description:Binding affinity against rat Alpha-2B adrenergic receptor using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  6.95nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-1B adrenergic receptor using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033111(6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity against rat Alpha-2B adrenergic receptor using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060964(5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]...)
Affinity DataKi:  7.90nMAssay Description:Binding affinity against human Alpha-2C adrenergic receptor using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  13.1nMAssay Description:Binding affinity against rat Alpha-2B adrenergic receptor using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060964(5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]...)
Affinity DataKi:  13.4nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-2A adrenergic receptor using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  16.6nMAssay Description:Binding affinity against human Alpha-2C adrenergic receptor using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  19.7nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiroperidol as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033111(6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...)
Affinity DataKi:  78nMAssay Description:Binding affinity against human Alpha-2C adrenergic receptor using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Bovine)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  83nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  94.9nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-2A adrenergic receptor using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  717nMAssay Description:Binding affinity against Dopamine receptor D1 using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033111(6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity against human adrenergic receptor subtype Alpha-2A adrenergic receptor using [3H]rauwolscine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  3.38E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  3.87E+3nMAssay Description:Binding affinity against adrenergic receptor subtype Beta-2 adrenergic receptor using [3H]DHA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50060965(2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...)
Affinity DataKi:  1.06E+4nMAssay Description:Binding affinity against Beta-1 adrenergic receptor using [3H]DHA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed