Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50036582
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061891(9-{3-[4-(6-Isothiocyanato-hexyl)-3,5-dimethyl-pipe...)
Affinity DataKd:  7.60nMAssay Description:Dissociation constant(KD) of [3H]WIN-35428 at saturation in rat caudate-putamen tissue pre-incubated in buffer at 100 nM (Dopamine transporter)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061891(9-{3-[4-(6-Isothiocyanato-hexyl)-3,5-dimethyl-pipe...)
Affinity DataKd:  17nMAssay Description:Dissociation constant(KD) of [3H]WIN-35428 at saturation in rat caudate-putamen tissue pre-incubated in buffer (Dopamine transporter)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061891(9-{3-[4-(6-Isothiocyanato-hexyl)-3,5-dimethyl-pipe...)
Affinity DataKd:  7.60nMAssay Description:Dissociation constant(KD) of [3H]WIN-35428 at saturation in rat caudate-putamen tissue pre-incubated in buffer at 100 nM (Dopamine transporter)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50019742(9-(3-(3,5-dimethylpiperazin-1-yl)propyl)-9H-carbaz...)
Affinity DataIC50: 58nMAssay Description:Binding affinity was evaluated using [3H]WIN-35428 binding to dopamine transporter (DAT) in rat caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061891(9-{3-[4-(6-Isothiocyanato-hexyl)-3,5-dimethyl-pipe...)
Affinity DataIC50: 87nMAssay Description:Binding affinity was evaluated using [3H]WIN-35428 binding to dopamine transporter (DAT) in rat caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50408286(CHEMBL2112760)
Affinity DataIC50: 244nMAssay Description:Binding affinity was evaluated using [3H]WIN-35428 binding to dopamine transporter (DAT) in rat caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061892(9-{3-[4-(3-Isothiocyanato-propyl)-3,5-dimethyl-pip...)
Affinity DataIC50: 523nMAssay Description:Binding affinity was evaluated using [3H]WIN-35428 binding to dopamine transporter (DAT) in rat caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061891(9-{3-[4-(6-Isothiocyanato-hexyl)-3,5-dimethyl-pipe...)
Affinity DataIC50: 707nMAssay Description:Binding affinity was evaluated using [3H]pentazocine binding to sigma-1 receptor from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50408286(CHEMBL2112760)
Affinity DataIC50: 897nMAssay Description:Binding affinity was evaluated using [3H]pentazocine binding to sigma-1 receptor from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061894(9-{3-[4-(2-Isothiocyanato-ethyl)-3,5-dimethyl-pipe...)
Affinity DataIC50: 949nMAssay Description:Binding affinity was evaluated using [3H]pentazocine binding to sigma-1 receptor from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061894(9-{3-[4-(2-Isothiocyanato-ethyl)-3,5-dimethyl-pipe...)
Affinity DataIC50: 1.25E+3nMAssay Description:Binding affinity was evaluated using [3H]WIN-35428 binding to dopamine transporter (DAT) in rat caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061895(3-Isothiocyanato-9-[3-(3,4,5-trimethyl-piperazin-1...)
Affinity DataIC50: 1.33E+3nMAssay Description:Binding affinity was evaluated using [3H]WIN-35428 binding to dopamine transporter (DAT) in rat caudate-putamenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50019742(9-(3-(3,5-dimethylpiperazin-1-yl)propyl)-9H-carbaz...)
Affinity DataIC50: 1.48E+3nMAssay Description:Binding affinity was evaluated using [3H]pentazocine binding to sigma-1 receptor from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50061892(9-{3-[4-(3-Isothiocyanato-propyl)-3,5-dimethyl-pip...)
Affinity DataIC50: 1.83E+3nMAssay Description:Binding affinity was evaluated using [3H]pentazocine binding to sigma-1 receptor from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2012
Entry Details Article
PubMed