Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50036656
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 3nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 3.86nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 3.90nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 5.62nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062372((2S,3R,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 14.4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062374((2R,3R,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 53nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062374((2R,3R,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 56nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 88nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062376((2R,3S,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 90nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 123nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062376((2R,3S,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 142nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 172nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 178nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 294nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 298nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 308nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 422nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 447nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062375((2S,3S,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 480nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062375((2S,3S,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 480nMAssay Description:Inhibition of [3H]paroxetine (0.2 nM) binding to 5-HT transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataIC50: 535nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataIC50: 623nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062375((2S,3S,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 835nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062375((2S,3S,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 835nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 1.05E+3nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062374((2R,3R,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062376((2R,3S,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 2.66E+4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062368((2S,3S,8R)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062375((2S,3S,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 3.74E+4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50062375((2S,3S,8S)-2-(Benzo[1,3]dioxol-5-yloxymethyl)-3-(4...)
Affinity DataIC50: 3.74E+4nMAssay Description:Inhibition of [3H]nisoxetine (0.5 nM) binding to Noradrenaline transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed