Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50038613
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.64E+5nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 3.42E+5nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 3.70E+5nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM84978(cid_5280459 | Quercitrin)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50009859((RS)-ibuprofen | CHEMBL521 | 2-(4-isobutylphenyl)p...)
Affinity DataIC50: 1.03E+6nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)
Affinity DataIC50: 1.02E+6nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM84978(cid_5280459 | Quercitrin)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM84978(cid_5280459 | Quercitrin)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 3.77E+6nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM84978(cid_5280459 | Quercitrin)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of bovine seminal microsomal COX1 assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.71E+6nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)