Compile Data Set for Download or QSAR
Report error Found 145 Enz. Inhib. hit(s) with all data for entry = 50007395
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.150nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataKi:  0.340nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062415(5-(4-Chloro-3-fluoro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  0.410nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062406(5-(3-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  0.430nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062409(5-(4-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataKi:  0.550nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062419(5-(3-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  0.690nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062417(5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  0.700nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062413(5-(3-Bromo-5-methyl-phenyl)-2,2,4-trimethyl-2,5-di...)
Affinity DataKi:  0.870nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062407(5-(3-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataKi:  1.10nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062414(5-(4-Chloro-3-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  1.20nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062421(5-(3,5-Dichloro-phenyl)-2,2,4-trimethyl-2,5-dihydr...)
Affinity DataKi:  1.70nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062416(5-(3-Fluoro-4-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataKi:  1.80nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062411(2,2,4-Trimethyl-5-p-tolyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataKi:  2.30nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062422(5-(3-Bromo-5-fluoro-phenyl)-2,2,4-trimethyl-2,5-di...)
Affinity DataKi:  2.40nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062405(2,2,4-Trimethyl-5-(3-trifluoromethyl-phenyl)-2,5-d...)
Affinity DataKi:  2.60nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataEC50:  2.90nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062423(5-(3,4-Dichloro-phenyl)-2,2,4-trimethyl-2,5-dihydr...)
Affinity DataKi:  3.40nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataKi:  3.5nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062410(2,2,4-Trimethyl-5-phenyl-2,5-dihydro-1H-6-oxa-1-az...)
Affinity DataKi:  3.60nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062418(5-(6-Bromo-pyridin-3-yl)-2,2,4-trimethyl-2,5-dihyd...)
Affinity DataKi:  3.90nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062403(5-(4-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataKi:  5.30nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  6.10nMAssay Description:Agonistic activity against Human androgen receptor(hAR) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062425(5-(4-Fluoro-3-trifluoromethyl-phenyl)-2,2,4-trimet...)
Affinity DataKi:  6.80nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062403(5-(4-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  8nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062407(5-(3-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  8nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062419(5-(3-Fluoro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  8nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity was determined on Human androgen receptor (hAR) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062424(1-[4-(2,2,4-Trimethyl-2,5-dihydro-1H-6-oxa-1-aza-c...)
Affinity DataKi:  8.80nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  10nMAssay Description:Agonist activity against Human glucocorticoid receptor(hGR) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062408(2,2,4-Trimethyl-5-(4-trifluoromethyl-phenyl)-2,5-d...)
Affinity DataKi:  11nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062405(2,2,4-Trimethyl-5-(3-trifluoromethyl-phenyl)-2,5-d...)
Affinity DataEC50:  13nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataKi:  13nMAssay Description:Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062412(5-(4-Methoxy-phenyl)-2,2,4-trimethyl-2,5-dihydro-1...)
Affinity DataKi:  13nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062420(5-(6-Bromo-pyridin-2-yl)-2,2,4-trimethyl-2,5-dihyd...)
Affinity DataKi:  13.8nMAssay Description:The binding affinity on Human progesterone receptor (hPR-A) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062414(5-(4-Chloro-3-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataEC50:  14nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataIC50: 14nMAssay Description:Antagonistic activity was determined in Human mineralocorticoid receptor(hMR) of CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062417(5-(4-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  14nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062409(5-(4-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataEC50:  14nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062416(5-(3-Fluoro-4-methyl-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataEC50:  16nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062413(5-(3-Bromo-5-methyl-phenyl)-2,2,4-trimethyl-2,5-di...)
Affinity DataEC50:  17nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062415(5-(4-Chloro-3-fluoro-phenyl)-2,2,4-trimethyl-2,5-d...)
Affinity DataEC50:  17nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062423(5-(3,4-Dichloro-phenyl)-2,2,4-trimethyl-2,5-dihydr...)
Affinity DataEC50:  18nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062406(5-(3-Chloro-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H...)
Affinity DataEC50:  18nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062425(5-(4-Fluoro-3-trifluoromethyl-phenyl)-2,2,4-trimet...)
Affinity DataEC50:  25nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062422(5-(3-Bromo-5-fluoro-phenyl)-2,2,4-trimethyl-2,5-di...)
Affinity DataEC50:  27nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataKi:  31nMAssay Description:Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062408(2,2,4-Trimethyl-5-(4-trifluoromethyl-phenyl)-2,5-d...)
Affinity DataEC50:  33nMAssay Description:Agonistic activity to the human progesterone receptor (hPR)assayed in CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50062407(5-(3-Bromo-phenyl)-2,2,4-trimethyl-2,5-dihydro-1H-...)
Affinity DataKi:  34nMAssay Description:Binding affinity was determined on Human glucocorticoid receptor (hAR) using progesterone as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataIC50: 37nMAssay Description:Antagonistic activity was determined in Human androgen receptor(hAR) of CV-1 cells in cotransfection assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Displayed 1 to 50 (of 145 total ) | Next | Last >>
Jump to: