Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50036702
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50000066(CHEMBL356688 | (2-Azepan-1-yl-ethyl)-[2-(3,4-dichl...)
Affinity DataKi:  0.170nMAssay Description:Inhibition of [3H]-NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50344263((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM73402(1-phenyl-1-cyclopentanecarboxylic acid 2-(diethyla...)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]- (+) - pentazocine binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM94507(SMR000326757 | Carbetapentane citrate | CHEMBL7323...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]- (+) - pentazocine binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50039197(1-Phenyl-cyclohexanecarboxylic acid 2-morpholin-4-...)
Affinity DataIC50: 44nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM83449(cid_9795678 | PHENCYCLIDINE | SMR001338811 | Phenc...)
Affinity DataIC50: 91nMAssay Description:Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50062779(1-Tricyclo[6.2.2.0*2,7*]dodeca-2(7),3,5-trien-1-yl...)
Affinity DataIC50: 319nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50062780(1-(1,3,4,8b-Tetrahydro-2H-biphenylen-4a-yl)-piperi...)
Affinity DataIC50: 330nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50062778(1-(3,4-Dihydro-2H-1,4-methano-naphthalen-1-yl)-pip...)
Affinity DataIC50: 365nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM83449(cid_9795678 | PHENCYCLIDINE | SMR001338811 | Phenc...)
Affinity DataIC50: 530nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50344263((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [3H]NANM binding to sigma receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50062780(1-(1,3,4,8b-Tetrahydro-2H-biphenylen-4a-yl)-piperi...)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50010618(3-(1-Propyl-piperidin-3-yl)-phenol | CHEMBL7393 | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50039197(1-Phenyl-cyclohexanecarboxylic acid 2-morpholin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50062778(1-(3,4-Dihydro-2H-1,4-methano-naphthalen-1-yl)-pip...)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50062779(1-Tricyclo[6.2.2.0*2,7*]dodeca-2(7),3,5-trien-1-yl...)
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of [3H]-TCP binding to PCP receptor obtained from tissue homogenate preparation of fresh whole rat brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed