Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50007440
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)
Affinity DataIC50: 2nMAssay Description:Inhibition of binding of [3H]glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50005044(CHEMBL58663 | (2R,4S)-5,7-Dichloro-4-(2-oxo-3-phen...)
Affinity DataIC50: 6nMAssay Description:Inhibition of binding of [3H]glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50005075(CHEMBL287327 | (2R,4S)-5,7-Dichloro-4-(3-phenyl-ur...)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of binding of [3H]glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50001263(CHEMBL114610 | 5,7-Dichloro-4-hydroxy-3-(4-hydroxy...)
Affinity DataIC50: 13nMAssay Description:Inhibition of binding of [3H]glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50005034(CHEMBL22895 | 7-Chloro-5-iodo-4-oxo-1,4-dihydro-qu...)
Affinity DataIC50: 32nMAssay Description:Inhibition of binding of [3H]glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50004952(CHEMBL31344 | 3-(2-Carboxy-ethyl)-4,6-dichloro-1H-...)
Affinity DataIC50: 140nMAssay Description:Inhibition of binding of [3H]glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cort...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed