Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50007509
TargetSigma non-opioid intracellular receptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064172(CHEMBL39900 | 1-benzylspiro[hexahydropyridine-4,2'...)
Affinity DataKi:  0.5nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H](+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[chroman-2,4'-piperidine] | 1'-benzy...)
Affinity DataKi:  0.620nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H](+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM29568([3H]-Minipress | [3H]-Furazosin | PRAZOSIN HYDROCH...)
Affinity DataKi:  1.05nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi:  1.40nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H](+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM29568([3H]-Minipress | [3H]-Furazosin | PRAZOSIN HYDROCH...)
Affinity DataKi:  2.93nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]prazosin from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.20nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H](+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  4.80nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]spiperone from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  6.10nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H](+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064176(METHOCTRAMINE | N,N''-Bis-[6-(2-methoxy-benzylamin...)
Affinity DataKi:  15nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]NMS from rat heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50044426(1-[1-(3-Isothiocyanato-phenyl)-cyclohexyl]-piperid...)
Affinity DataKi:  16nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H](+)-NANM in the presence of 5 uM haloperidol from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064173(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi:  20nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H](+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064175(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi:  25nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H](+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064176(METHOCTRAMINE | N,N''-Bis-[6-(2-methoxy-benzylamin...)
Affinity DataKi:  998nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]NMS from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi:  2.70E+3nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]NMS from rat heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi:  5.50E+3nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]spiperone from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  8.50E+3nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H](+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[chroman-2,4'-piperidine] | 1'-benzy...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]spiperone from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064175(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]NMS from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064173(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]prazosin from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H](+)-NANM in the presence of 5 uM haloperidol from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[chroman-2,4'-piperidine] | 1'-benzy...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H](+)-NANM in the presence of 5 uM haloperidol from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064175(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]spiperone from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064173(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]spiperone from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064173(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[chroman-2,4'-piperidine] | 1'-benzy...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]NMS from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[chroman-2,4'-piperidine] | 1'-benzy...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]NMS from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064172(CHEMBL39900 | 1-benzylspiro[hexahydropyridine-4,2'...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064172(CHEMBL39900 | 1-benzylspiro[hexahydropyridine-4,2'...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H](+)-NANM in the presence of 5 uM haloperidol from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[chroman-2,4'-piperidine] | 1'-benzy...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]NMS from rat heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064175(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]NMS from rat heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064172(CHEMBL39900 | 1-benzylspiro[hexahydropyridine-4,2'...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]NMS from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064175(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H](+)-NANM in the presence of 5 uM haloperidol from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064175(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064173(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]NMS from rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064175(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]prazosin from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[chroman-2,4'-piperidine] | 1'-benzy...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]prazosin from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064172(CHEMBL39900 | 1-benzylspiro[hexahydropyridine-4,2'...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]prazosin from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(CHEMBL41830 | CHEMBL554874 | 1'-benzylspiro[1,2,3,...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]prazosin from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064173(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]NMS from rat heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064173(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H](+)-NANM in the presence of 5 uM haloperidol from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064172(CHEMBL39900 | 1-benzylspiro[hexahydropyridine-4,2'...)
Affinity DataKi:  1.04E+4nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]spiperone from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50064172(CHEMBL39900 | 1-benzylspiro[hexahydropyridine-4,2'...)
Affinity DataKi:  1.08E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]NMS from rat heartMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed