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Found
113
Enz. Inhib. hit(s) with all data for entry = 5152
Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81811
(MK-912 | NSC_123679 | CAS_123679 | L-657,743)
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Affinity Data
Ki: 0.0700nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019492
(RX821002 | CHEMBL10332 | 2-(2-methoxy-2,3-dihydrob...)
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Affinity Data
Ki: 0.360nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 0.550nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
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Date in BDB:
3/4/2012
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Article
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019492
(RX821002 | CHEMBL10332 | 2-(2-methoxy-2,3-dihydrob...)
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Affinity Data
Ki: 0.620nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019492
(RX821002 | CHEMBL10332 | 2-(2-methoxy-2,3-dihydrob...)
Copy SMILES
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Affinity Data
Ki: 0.790nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81811
(MK-912 | NSC_123679 | CAS_123679 | L-657,743)
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Affinity Data
Ki: 0.850nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81811
(MK-912 | NSC_123679 | CAS_123679 | L-657,743)
Copy SMILES
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Affinity Data
Ki: 0.890nM
More data for this Ligand-Target Pair
Target Info
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PC cid
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 1.20nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
PC sid
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
Copy SMILES
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Affinity Data
Ki: 1.20nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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In Depth
Date in BDB:
3/4/2012
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Article
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019492
(RX821002 | CHEMBL10332 | 2-(2-methoxy-2,3-dihydrob...)
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Affinity Data
Ki: 1.62nM
More data for this Ligand-Target Pair
Target Info
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(naphtaline | CHEMBL16293 | naphtalene | naftalina ...)
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Affinity Data
Ki: 3.31nM
More data for this Ligand-Target Pair
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KEGG
PC cid
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Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50241196
(CHEMBL397901 | (R)-5-(1-(2,3-dimethylphenyl)ethyl)...)
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Affinity Data
Ki: 3.39nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(naphtaline | CHEMBL16293 | naphtalene | naftalina ...)
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Affinity Data
Ki: 4.57nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
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Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(SMR000059324 | Oxymetazoline | cid_66259 | 6-tert-...)
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Affinity Data
Ki: 7.24nM
More data for this Ligand-Target Pair
Target Info
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KEGG
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PDB
3D Structure (crystal)
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(naphtaline | CHEMBL16293 | naphtalene | naftalina ...)
Copy SMILES
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Affinity Data
Ki: 7.76nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
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In Depth
Date in BDB:
3/4/2012
Entry Details
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM85232
(CAS_67249-51-8 | ICI 106270)
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Affinity Data
Ki: 7.94nM
More data for this Ligand-Target Pair
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In Depth
Date in BDB:
3/4/2012
Entry Details
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81926
(p-AMINOCLONIDINE | CAS_66711-21-5 | NSC_51763 | Am...)
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Affinity Data
Ki: 7.94nM
More data for this Ligand-Target Pair
Target Info
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DrugBank
KEGG
PC cid
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Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(naphtaline | CHEMBL16293 | naphtalene | naftalina ...)
Copy SMILES
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Affinity Data
Ki: 9.33nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
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Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019729
(A-54741 | CHEMBL7169 | (S)-5-(4,5-Dihydro-1H-imida...)
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Affinity Data
Ki: 9.77nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
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PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(CHEMBL10316 | Idazoxan | US8633208, Idazoxan | 4,5...)
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Affinity Data
Ki: 9.77nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50001922
(Naphazoline | Albalon | Opcon | CHEMBL1706 | Nafaz...)
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Affinity Data
Ki: 11.5nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
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CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50241196
(CHEMBL397901 | (R)-5-(1-(2,3-dimethylphenyl)ethyl)...)
Copy SMILES
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Affinity Data
Ki: 13.2nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM85233
(CAS_81447-78-1 | Levlofexidine)
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Affinity Data
Ki: 14.4nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...)
Copy SMILES
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Affinity Data
Ki: 15.1nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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CHEMBL
DrugBank
KEGG
PC cid
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Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50027056
(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
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Affinity Data
Ki: 15.5nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
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CHEMBL
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(SMR000059324 | Oxymetazoline | cid_66259 | 6-tert-...)
Copy SMILES
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Affinity Data
Ki: 15.5nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
GoogleScholar
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DrugBank
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
PDB
3D Structure (crystal)
Copy reaction URL
Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50159249
(naphtaline | CHEMBL16293 | naphtalene | naftalina ...)
Copy SMILES
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Affinity Data
Ki: 17.0nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50001922
(Naphazoline | Albalon | Opcon | CHEMBL1706 | Nafaz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 17.0nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
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CHEMBL
DrugBank
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(CHEMBL10316 | Idazoxan | US8633208, Idazoxan | 4,5...)
Copy SMILES
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Affinity Data
Ki: 19.9nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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CHEMBL
KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81984
(NSC_3519 | CAS_29110-47-2 | Guanfacine)
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Affinity Data
Ki: 20.4nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Copy SMILES
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Affinity Data
Ki: 20.4nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50001922
(Naphazoline | Albalon | Opcon | CHEMBL1706 | Nafaz...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20.9nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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CHEMBL
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81926
(p-AMINOCLONIDINE | CAS_66711-21-5 | NSC_51763 | Am...)
Copy SMILES
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Affinity Data
Ki: 21.4nM
More data for this Ligand-Target Pair
Target Info
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KEGG
PC cid
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Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81979
(Guanabenz | NSC_3517 | NSC_65636 | CAS_5051-62-7 |...)
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Affinity Data
Ki: 21.9nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...)
Copy SMILES
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Affinity Data
Ki: 24.0nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
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CHEMBL
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KEGG
PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30712
(SMR000059324 | Oxymetazoline | cid_66259 | 6-tert-...)
Copy SMILES
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Affinity Data
Ki: 25.7nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
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PC cid
PC sid
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Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
PDB
3D Structure (crystal)
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM30703
(SMR000058526 | 2-[(4-tert-butyl-2,6-dimethyl-pheny...)
Copy SMILES
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Affinity Data
Ki: 25.7nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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KEGG
PC cid
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Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
Copy reaction URL
Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM81926
(p-AMINOCLONIDINE | CAS_66711-21-5 | NSC_51763 | Am...)
Copy SMILES
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Affinity Data
Ki: 29.5nM
More data for this Ligand-Target Pair
Target Info
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PC cid
PC sid
Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2C adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM29568
([3H]-Minipress | [3H]-Furazosin | PRAZOSIN HYDROCH...)
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Affinity Data
Ki: 30.9nM
More data for this Ligand-Target Pair
Target Info
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CHEMBL
DrugBank
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PC cid
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50027056
(CHEMBL32573 | Tramazoline | Imidazolidin-2-ylidene...)
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Ki: 31.6nM
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Date in BDB:
3/4/2012
Entry Details
Article
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM31046
(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
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Ki: 33.1nM
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Date in BDB:
3/4/2012
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Article
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50241196
(CHEMBL397901 | (R)-5-(1-(2,3-dimethylphenyl)ethyl)...)
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Affinity Data
Ki: 33.9nM
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Date in BDB:
3/4/2012
Entry Details
Article
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Ki: 36.3nM
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Date in BDB:
3/4/2012
Entry Details
Article
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50019848
(CHEMBL10316 | Idazoxan | US8633208, Idazoxan | 4,5...)
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Ki: 37.1nM
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Date in BDB:
3/4/2012
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-2-imidazoline | 2-(2,6-dic...)
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Ki: 40.7nM
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Date in BDB:
3/4/2012
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Article
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PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM34572
(UK 14,304 | SMR000058355 | CHEMBL844 | cid_2435 | ...)
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Ki: 43.6nM
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Date in BDB:
3/4/2012
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3D Structure (crystal)
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Target
Alpha-2A adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-2-imidazoline | 2-(2,6-dic...)
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Affinity Data
Ki: 61.7nM
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50013515
(yohimbic acid methyl ester | 17alpha-hydroxyyohimb...)
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Affinity Data
Ki: 61.7nM
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KEGG
PC cid
PC sid
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In Depth
Date in BDB:
3/4/2012
Entry Details
Article
Copy BDB DOI
PubMed
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Target
Alpha-2A adrenergic receptor
(Mouse)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM50016897
(2-(2,6-dichloroanilino)-2-imidazoline | 2-(2,6-dic...)
Copy SMILES
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Affinity Data
Ki: 61.7nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/TrEMBL
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Similars
In Depth
Date in BDB:
3/4/2012
Entry Details
Article
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PubMed
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Target
Alpha-2B adrenergic receptor
(Human)
Roche Bioscience
Curated by
PDSP K
i
Database
Ligand
BDBM85234
(NSC_133621 | CAS_81167-16-0 | IMILOXAN)
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Ki: 67.6nM
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Date in BDB:
3/4/2012
Entry Details
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