Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 1290
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10687((3aS)-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,...)
Affinity DataIC50: 2nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10681((-)-(3aS)-3a-Methyl-1,2,3,3a,8,8a-hexahydropyrrol[...)
Affinity DataIC50: 2.40nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10689((3aS)-1,3a-dimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,...)
Affinity DataIC50: 6.80nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10684((3aS)-1,8-dibenzyl-3a-methyl-1H,2H,3H,3aH,8H,8aH-p...)
Affinity DataIC50: 8.10nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10690((3aS)-1-benzyl-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-p...)
Affinity DataIC50: 10.4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10681((-)-(3aS)-3a-Methyl-1,2,3,3a,8,8a-hexahydropyrrol[...)
Affinity DataIC50: 10.9nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10686((3aS)-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,...)
Affinity DataIC50: 13.8nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10608(CHEMBL306319 | Physostigmine Carbamate 15a | Physo...)
Affinity DataIC50: 16nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10687((3aS)-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,...)
Affinity DataIC50: 21nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10691(CHEMBL80221 | (3aS)-8-benzyl-1,3a-dimethyl-1H,2H,3...)
Affinity DataIC50: 21.8nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10679((3aS)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]...)
Affinity DataIC50: 22.1nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10622((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 24nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10608(CHEMBL306319 | Physostigmine Carbamate 15a | Physo...)
Affinity DataIC50: 27.9nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10688(CHEMBL418917 | (3aS)-1,3a-dimethyl-1H,2H,3H,3aH,8H...)
Affinity DataIC50: 40.8nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10689((3aS)-1,3a-dimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,...)
Affinity DataIC50: 56.7nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10691(CHEMBL80221 | (3aS)-8-benzyl-1,3a-dimethyl-1H,2H,3...)
Affinity DataIC50: 161nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10680((+)9 | (3aR)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 231nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10682((+)10 | (3aR)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrol...)
Affinity DataIC50: 237nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10690((3aS)-1-benzyl-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-p...)
Affinity DataIC50: 330nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10683((3aS)-1,8-dibenzyl-3a-methyl-1H,2H,3H,3aH,8H,8aH-p...)
Affinity DataIC50: 513nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10688(CHEMBL418917 | (3aS)-1,3a-dimethyl-1H,2H,3H,3aH,8H...)
Affinity DataIC50: 516nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10686((3aS)-3a,8-dimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,...)
Affinity DataIC50: 612nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10685((+)19 | (3aR)-1,8-dibenzyl-3a-methyl-1H,2H,3H,3aH,...)
Affinity DataIC50: 776nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10679((3aS)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]...)
Affinity DataIC50: 897nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10680((+)9 | (3aR)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 952nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10684((3aS)-1,8-dibenzyl-3a-methyl-1H,2H,3H,3aH,8H,8aH-p...)
Affinity DataIC50: 1.09E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10622((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 1.30E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10682((+)10 | (3aR)-3a-methyl-1H,2H,3H,3aH,8H,8aH-pyrrol...)
Affinity DataIC50: 1.49E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10609((3aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 2.49E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10676(CHEMBL75919 | (3aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,...)
Affinity DataIC50: 3.50E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10685((+)19 | (3aR)-1,8-dibenzyl-3a-methyl-1H,2H,3H,3aH,...)
Affinity DataIC50: 3.56E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10609((3aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 9.89E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10676(CHEMBL75919 | (3aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,...)
Affinity DataIC50: 2.35E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM10683((3aS)-1,8-dibenzyl-3a-methyl-1H,2H,3H,3aH,8H,8aH-p...)
Affinity DataIC50: 4.11E+4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2006
Entry Details Article
PubMed