Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50036640
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066062(1,3-Bis-(4-sec-butyl-phenyl)-imidazolidin-2-yliden...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066059(1,3-Bis-(4-sec-butyl-phenyl)-tetrahydro-pyrimidin-...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066066(CHEMBL281724 | (S)-1-[4-(Benzothiazol-2-yl-methyl-...)
Affinity DataIC50: 260nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066067(2-(4-tert-Butyl-phenyl)-6-isopropyl-3,4-dihydro-2H...)
Affinity DataIC50: 460nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066069(N-(4-tert-Butyl-benzyl)-N-(4-sec-butyl-phenyl)-gua...)
Affinity DataIC50: 620nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066052((3-sec-Butyl-phenyl)-[1-(4-sec-butyl-phenyl)-imida...)
Affinity DataIC50: 780nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066057(CHEMBL320199 | CHEMBL110909 | N,N'-Bis-(4-sec-buty...)
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066060(N,N'-Bis-(4-sec-butyl-phenyl)-N,N'-dimethyl-guanid...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066068(N-Acenaphthen-5-yl-N'-(4-methoxy-naphthalen-1-yl)-...)
Affinity DataIC50: 1.64E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066061(1-(4-sec-Butyl-phenyl)-5-(4-isopropyl-phenyl)-imid...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066063(9,15-Dioxa-2,4-diaza-tricyclo[14.2.2.2*5,8*]docosa...)
Affinity DataIC50: 2.90E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066053(N,N'-Bis-(4-ethoxy-phenyl)-guanidine; hydrochlorid...)
Affinity DataIC50: 3.28E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066055(3-Phenyl-1,2,3,4-tetrahydro-quinazolin-2-ylamine; ...)
Affinity DataIC50: 9.95E+3nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010769(CHEMBL556117 | CHEMBL77675 | N,N'-Diphenyl-guanidi...)
Affinity DataIC50: 1.40E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010804(CHEMBL554829 | CHEMBL82144 | 1,3-Diphenyl-imidazol...)
Affinity DataIC50: 1.47E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066070(2-Phenyl-3,4-dihydro-2H-quinoline-1-carboxamidine;...)
Affinity DataIC50: 1.76E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066056(1,5-Diphenyl-imidazolidin-(2Z)-ylideneamine; hydro...)
Affinity DataIC50: 2.40E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066065(1,3-Diphenyl-tetrahydro-pyrimidin-2-ylideneamine; ...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066064(Phenyl-[1-phenyl-imidazolidin-(2E)-ylidene]-amine;...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066054(11,12-Dihydro-6H-dibenzo[b,f]azocine-5-carboxamidi...)
Affinity DataIC50: 3.80E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066071(N-Benzyl-N-phenyl-guanidine; hydrochloride | CHEMB...)
Affinity DataIC50: 5.30E+4nMAssay Description:In vitro inhibition of [14C]- guanidinium influx in Chinese hamster ovary (CHO) cells expressing rat brain sodium channel type IIA (CNaIIA-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed