Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50036648
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066417(N-(4-Benzyloxy-phenyl)-N'-(4-tert-butyl-phenyl)-gu...)
Affinity DataIC50: 110nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066427(N,N'-Bis-(4-butyl-phenyl)-guanidine | CHEMBL109210)
Affinity DataIC50: 130nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066420(N-(4-Benzyloxy-phenyl)-N'-(4-butyl-phenyl)-guanidi...)
Affinity DataIC50: 140nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066423(N,N'-Bis-(4-butoxy-phenyl)-guanidine | CHEMBL32650...)
Affinity DataIC50: 190nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066425(N,N'-Bis-(4-phenoxy-phenyl)-guanidine | CHEMBL1125...)
Affinity DataIC50: 430nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010754(CHEMBL81626 | N,N'-Bis-(4-isopropyl-phenyl)-guanid...)
Affinity DataIC50: 460nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066428(N-Acenaphthen-5-yl-N'-(4-sec-butyl-phenyl)-guanidi...)
Affinity DataIC50: 680nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066057(CHEMBL320199 | CHEMBL110909 | N,N'-Bis-(4-sec-buty...)
Affinity DataIC50: 800nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066419(N,N'-Bis-(4-hexyl-phenyl)-guanidine | CHEMBL326741)
Affinity DataIC50: 830nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066424(N,N'-Bis-(4-phenylsulfanyl-phenyl)-guanidine | CHE...)
Affinity DataIC50: 840nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066422(N,N'-Bis-biphenyl-4-yl-guanidine | CHEMBL326130)
Affinity DataIC50: 850nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010736(CHEMBL78083 | N,N'-Bis-(4-ethyl-phenyl)-guanidine)
Affinity DataIC50: 1.39E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066421(N,N'-Bis-(4-tert-butyl-phenyl)-guanidine | CHEMBL3...)
Affinity DataIC50: 1.54E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066068(N-Acenaphthen-5-yl-N'-(4-methoxy-naphthalen-1-yl)-...)
Affinity DataIC50: 1.64E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066429(N-(4-Butoxy-phenyl)-N'-[4-(4-hydroxy-butyl)-phenyl...)
Affinity DataIC50: 1.78E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066430(CHEMBL28854 | 2-(4-Methyl-piperazin-1-yl)-5-(2,3,5...)
Affinity DataIC50: 2.55E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM30705(SMR000058231 | CHEMBL744 | cid_5070 | MLS000069369...)
Affinity DataIC50: 4.73E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50066426(N,N'-Bis-[4-(4-hydroxy-butyl)-phenyl]-guanidine | ...)
Affinity DataIC50: 8.19E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetSodium channel protein type 2 subunit alpha(Rat)
Cambridge Neuroscience

Curated by ChEMBL
LigandPNGBDBM50010743(N,N'-Di-p-tolyl-guanidine)
Affinity DataIC50: 9.21E+3nMAssay Description:Sodium channel block, determined by % block of [14C]guanidinium flux in CHO line expressing rat type IIA sodium channels derived from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed