Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50036649
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.300nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366558(ZK-98299 | ONAPRISTONE)
Affinity DataIC50: 2.20nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066524(6-(3-Fluoro-5-nitro-phenyl)-2,2,4-trimethyl-1,2-di...)
Affinity DataKi:  5nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066526(3-Fluoro-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6...)
Affinity DataKi:  10nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066522(6-(3,5-difluorophenyl)-2,2,4-trimethyl-1,2-dihydro...)
Affinity DataKi:  10nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50366558(ZK-98299 | ONAPRISTONE)
Affinity DataKi:  18nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066529(3-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)benzon...)
Affinity DataKi:  19nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066523(2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...)
Affinity DataKi:  20nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066526(3-Fluoro-5-(2,2,4-trimethyl-1,2-dihydro-quinolin-6...)
Affinity DataIC50: 30nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066529(3-(2,2,4-trimethyl-1,2-dihydroquinolin-6-yl)benzon...)
Affinity DataIC50: 38nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066523(2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...)
Affinity DataIC50: 42nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066524(6-(3-Fluoro-5-nitro-phenyl)-2,2,4-trimethyl-1,2-di...)
Affinity DataIC50: 70nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066522(6-(3,5-difluorophenyl)-2,2,4-trimethyl-1,2-dihydro...)
Affinity DataIC50: 79nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066527(2,2,4-Trimethyl-6-phenyl-1,2-dihydro-quinoline | 2...)
Affinity DataKi:  133nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066528(6-(3-fluorophenyl)-2,2,4-trimethyl-1,2-dihydroquin...)
Affinity DataKi:  182nMAssay Description:Binding affinity against Baculovirus-Expressed hPR-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066528(6-(3-fluorophenyl)-2,2,4-trimethyl-1,2-dihydroquin...)
Affinity DataIC50: 750nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50066527(2,2,4-Trimethyl-6-phenyl-1,2-dihydro-quinoline | 2...)
Affinity DataIC50: 783nMAssay Description:In vitro antagonist activity against human progesterone receptor isoform B(hPR-B) in mammalian(CV-1) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed