Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 1932
TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM15239(SB4 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-...)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM15238(SB3 | C14316 | 4-[1-(cyclopropylmethyl)-4-(4-fluor...)
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Rat)
University of Texas At Dallas

LigandPNGBDBM15239(SB4 | 4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-...)
Affinity DataIC50: 1.80E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Rat)
University of Texas At Dallas

LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 2.70E+4nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
University of Texas At Dallas

LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Rat)
University of Texas At Dallas

LigandPNGBDBM15237(SB2 | CHEMBL96741 | 4-[1-(cyclopropylmethyl)-4-(4-...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Rat)
University of Texas At Dallas

LigandPNGBDBM15238(SB3 | C14316 | 4-[1-(cyclopropylmethyl)-4-(4-fluor...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Rat)
University of Texas At Dallas

LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataIC50: 1.00E+6nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2007
Entry Details Article
PubMed