Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50007824
TargetMu-type opioid receptor(Guinea pig)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataEC50:  3.90E+4nMAssay Description:Tested for electrically induced smooth muscle contractions from guinea pig ileum expressed in mu opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50084127((4S,7S,13S)-13-[(2S,3R)-2-Amino-3-(4-hydroxy-2,6-d...)
Affinity DataEC50:  1.80nMAssay Description:Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068136(3-[(4-Benzyl-piperazin-1-yl)-phenyl-methyl]-phenol...)
Affinity DataEC50:  1.25E+3nMAssay Description:Tested for electrically induced smooth muscle contractions from guinea pig ileum expressed in mu opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068136(3-[(4-Benzyl-piperazin-1-yl)-phenyl-methyl]-phenol...)
Affinity DataEC50:  174nMAssay Description:Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataEC50:  210nMAssay Description:Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataEC50:  210nMAssay Description:Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataEC50:  7.60E+3nMAssay Description:Tested for electrically induced smooth muscle contractions from guinea pig ileum expressed in mu opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50039026(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 0.310nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataIC50: 1.06nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068133((4S,7S,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity was measured against cloned human Opioid receptor delta 1 (wild-type,Wt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068133((4S,7S,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068133((4S,7S,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity was measured against mutated human Opioid receptor delta 1 (W248L)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity was measured against cloned human Opioid receptor delta 1 (wild-type,Wt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50084127((4S,7S,13S)-13-[(2S,3R)-2-Amino-3-(4-hydroxy-2,6-d...)
Affinity DataIC50: 5nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity was measured against cloned human Opioid receptor delta 1 (wild-type,Wt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataIC50: 8.40nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataIC50: 8.40nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50039026(4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-y...)
Affinity DataIC50: 9.70nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataIC50: 17nMAssay Description:Binding affinity was measured against mutated human Opioid receptor delta 1 (W248L)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068140(3-[(4-Benzyl-piperazin-1-yl)-biphenyl-4-yl-methyl]...)
Affinity DataIC50: 31nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068136(3-[(4-Benzyl-piperazin-1-yl)-phenyl-methyl]-phenol...)
Affinity DataIC50: 34nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataIC50: 49nMAssay Description:Binding affinity was measured against mutated human Opioid receptor delta 1 (W248L)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068138((4S,7S,13S)-13-[(S)-2-Amino-3-(4-methoxy-phenyl)-p...)
Affinity DataIC50: 230nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068135(3-[1-(4-Benzyl-piperazin-1-yl)-3-methyl-butyl]-phe...)
Affinity DataIC50: 420nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068136(3-[(4-Benzyl-piperazin-1-yl)-phenyl-methyl]-phenol...)
Affinity DataIC50: 500nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068133((4S,7S,13S)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataIC50: 609nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 609nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068139(3-[1-(4-Benzyl-piperazin-1-yl)-ethyl]-phenol | CHE...)
Affinity DataIC50: 610nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068139(3-[1-(4-Benzyl-piperazin-1-yl)-ethyl]-phenol | CHE...)
Affinity DataIC50: 780nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068141(1-Benzyl-4-[(4-tert-butyl-phenyl)-(3-methoxy-pheny...)
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068135(3-[1-(4-Benzyl-piperazin-1-yl)-3-methyl-butyl]-phe...)
Affinity DataIC50: 2.10E+3nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataIC50: 2.50E+3nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50084127((4S,7S,13S)-13-[(2S,3R)-2-Amino-3-(4-hydroxy-2,6-d...)
Affinity DataIC50: 4.30E+3nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068134(3-(4-Benzyl-piperazin-1-ylmethyl)-phenol | CHEMBL1...)
Affinity DataIC50: 6.40E+3nMAssay Description:Binding affinity was measured against Opioid receptor delta 1 using [3H]p-Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068141(1-Benzyl-4-[(4-tert-butyl-phenyl)-(3-methoxy-pheny...)
Affinity DataIC50: 8.00E+3nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068134(3-(4-Benzyl-piperazin-1-ylmethyl)-phenol | CHEMBL1...)
Affinity DataIC50: 8.10E+3nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068138((4S,7S,13S)-13-[(S)-2-Amino-3-(4-methoxy-phenyl)-p...)
Affinity DataIC50: 1.10E+4nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataIC50: 1.10E+4nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068132(SL-3111 | 3-[(4-Benzyl-piperazin-1-yl)-(4-tert-but...)
Affinity DataIC50: 1.10E+4nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50068140(3-[(4-Benzyl-piperazin-1-yl)-biphenyl-4-yl-methyl]...)
Affinity DataIC50: 2.70E+4nMAssay Description:Binding affinity was measured against Opioid receptor mu 1 using [3H]-DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed