Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50007989
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069883((2,6-Diisopropyl-phenylcarbamoyl)-methanesulfonic ...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069886((2,6-Diisopropyl-phenylcarbamoyl)-methanesulfonic ...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069893((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid 1-me...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069890((2,6-Diisopropyl-phenylsulfamoyl)-thioacetic acid ...)
Affinity DataIC50: 36nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069902((2,6-Diisopropyl-phenylsulfamoyl)-thioacetic acid ...)
Affinity DataIC50: 73nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069873((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid dode...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069901((2,6-Diisopropyl-phenylsulfamoyl)-thioacetic acid ...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069887((2,6-Diisopropyl-phenylsulfamoyl)-thioacetic acid ...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069880(N-Benzyl-2-(2,6-diisopropyl-phenylsulfamoyl)-N-iso...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069875((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid tetr...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069891(Acylphosphonamide anlogue | CHEMBL316728)
Affinity DataIC50: 290nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069871(2-(2,6-Diisopropyl-phenylsulfamoyl)-N-dodecyl-acet...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069882(N-(2,6-Diisopropyl-phenyl)-2-(2,6-diisopropyl-phen...)
Affinity DataIC50: 350nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069878(Acylphosphonamide anlogue | CHEMBL317779)
Affinity DataIC50: 740nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069884((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid 2,4,...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069877((2,6-Diisopropyl-phenylsulfamoyl)-thioacetic acid ...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069896((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid 2,6-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069903(2-(2,6-Diisopropyl-phenylsulfamoyl)-N-(1-phenyl-cy...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069895((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid decy...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069898((2,4,6-Triisopropyl-phenylsulfamoyl)-acetic acid 2...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069905((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid hexy...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069899((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid octy...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069892((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid ethy...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069888(Acylphosphonamide anlogue | CHEMBL100996)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069874((Benzhydryl-carbamoyl)-methanesulfonic acid 2,6-di...)
Affinity DataIC50: 1.80E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069872(Acylphosphonamide analogue | CHEMBL419530)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069904((2,6-Diisopropyl-phenylsulfamoyl)-acetic acid 2,4,...)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069876(Dodecylcarbamoyl-methanesulfonic acid 2,6-diisopro...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069889(2-(2,6-Diisopropyl-phenylsulfamoyl)-N,N-dioctyl-ac...)
Affinity DataIC50: 4.20E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069897([2-(2,4,6-Triisopropyl-phenyl)-acetyl]-phosphorami...)
Affinity DataIC50: 4.80E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069894((2,6-Diisopropyl-phenylsulfamoyl)-thioacetic acid ...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069885([2-(2,4,6-Triisopropyl-phenyl)-acetyl]-phosphorami...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069881(2-(2,6-Diisopropyl-phenylsulfamoyl)-N-hexyl-acetam...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50040468(Sodium salt of CarboSulfamic acid Bis-(2,6-diisopr...)
Affinity DataIC50: 5.20E+3nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069900(CHEMBL101309 | [2-(2,4,6-Triisopropyl-phenyl)-acet...)
Affinity DataIC50: 1.20E+4nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50069879((2,6-Diisopropyl-phenylsulfamoyl)-thioacetic acid ...)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of ACAT by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed