Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50007992
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069968(Sodium; 9-fluoro-3-phenyl-5,6-dihydro-benzo[c]acri...)
Affinity DataKi:  8.30nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069950(Sodium; 9-fluoro-3-o-tolyl-5,6-dihydro-benzo[c]acr...)
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069959(Sodium; 6-fluoro-2-(2'-fluoro-biphenyl-4-yl)-3-met...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069939(Sodium; 9-fluoro-3-p-tolyl-6H-thiochromeno[4,3-b]q...)
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069951(Sodium; 9-fluoro-3-phenyl-6H-thiochromeno[4,3-b]qu...)
Affinity DataKi:  17nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069943(Sodium; 9-fluoro-3-(2-methoxy-phenyl)-5,6-dihydro-...)
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069948(Sodium; 9-fluoro-3-(3-methoxy-phenyl)-5,6-dihydro-...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069958(Sodium; 9-fluoro-3-o-tolyl-5H-6-thia-12-aza-benzo[...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069941(Sodium; 9-fluoro-3-o-tolyl-6H-thiochromeno[4,3-b]q...)
Affinity DataKi:  27nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069971(Sodium; 3-phenyl-9-trifluoromethyl-5,6-dihydro-ben...)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069940(Sodium; 9-fluoro-3-(2-fluoro-phenyl)-5,6-dihydro-b...)
Affinity DataKi:  34nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069960(Sodium; 9-fluoro-3-m-tolyl-6H-thiochromeno[4,3-b]q...)
Affinity DataKi:  37nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069949(Sodium; 9-fluoro-3-(2-trifluoromethyl-phenyl)-5,6-...)
Affinity DataKi:  40nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069944(Sodium; 9-fluoro-3-p-tolyl-5,6-dihydro-benzo[c]acr...)
Affinity DataKi:  40nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069966(Sodium; 9-fluoro-3-(3-trifluoromethyl-phenyl)-5,6-...)
Affinity DataKi:  43nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069957(Sodium; 9-fluoro-3-phenyl-6H-chromeno[4,3-b]quinol...)
Affinity DataKi:  48nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069970(Sodium; 9-fluoro-3-thiophen-3-yl-5,6-dihydro-benzo...)
Affinity DataKi:  52nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069947(Sodium; 9-fluoro-3-(4-methoxy-phenyl)-5,6-dihydro-...)
Affinity DataKi:  55nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069961(Sodium; 9-fluoro-3-m-tolyl-5,6-dihydro-benzo[c]acr...)
Affinity DataKi:  59nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069973(Sodium; 9-fluoro-3-m-tolyl-5,6-dihydro-benzo[b][1,...)
Affinity DataKi:  81nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069946(Sodium; 9-fluoro-3-m-tolyl-5H-6-thia-12-aza-benzo[...)
Affinity DataKi:  135nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069952(Sodium; 9-fluoro-5,5-dioxo-3-phenyl-5,6-dihydro-5l...)
Affinity DataKi:  139nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069945(Sodium; 9-fluoro-3-(3-methoxy-phenyl)-5,6-dihydro-...)
Affinity DataKi:  160nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069972(Sodium; 9-fluoro-3-phenyl-5H-6-thia-12-aza-benzo[a...)
Affinity DataKi:  170nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069942(Sodium; 9-fluoro-3-thiazol-2-yl-5,6-dihydro-benzo[...)
Affinity DataKi: >180nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069962(Sodium; 8-fluoro-2-phenyl-4,5-dihydro-1-thia-11-az...)
Affinity DataKi: >182nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069963(Sodium; 9-fluoro-3-furan-3-yl-5,6-dihydro-benzo[c]...)
Affinity DataKi:  190nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069969(Sodium; 9-fluoro-3-phenyl-5H-6-oxa-12-aza-benzo[a]...)
Affinity DataKi: >204nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069964(Sodium; 9-fluoro-5-oxo-3-phenyl-5,6-dihydro-5lambd...)
Affinity DataKi:  206nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069967(Sodium; 9-fluoro-3-p-tolyl-5H-6-thia-12-aza-benzo[...)
Affinity DataKi:  218nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069965(Sodium; 9-fluoro-4-phenyl-5,6-dihydro-benzo[c]acri...)
Affinity DataKi:  300nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069953(Sodium; 9-fluoro-3-(4-trifluoromethyl-phenyl)-5,6-...)
Affinity DataKi:  370nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069974(Sodium; 9-fluoro-3-phenyl-5,6-dihydro-2,4,12-triaz...)
Affinity DataKi:  380nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069954(Sodium; 9-fluoro-3-phenyl-5,6-dihydro-benzo[b][1,7...)
Affinity DataKi:  409nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069956(Sodium; 9-fluoro-4-phenoxy-5,6-dihydro-benzo[c]acr...)
Affinity DataKi:  962nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50069955(Sodium; 9-fluoro-2-phenyl-5,6-dihydro-benzo[c]acri...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human recombinant dihydroorotate dehydrogenase (DHODase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed