Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50034937
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070679((S)-2-[(S)-2-{(S)-3-(4-Fluoro-phenyl)-2-[(E)-(3-ph...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070674(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070677(2-[(S)-1-(2-Amino-3-methyl-butyrylamino)-2-(4-fluo...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070676(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50366502(CHEMBL1790240)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070673(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070656(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070670(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070669(2-[(S)-1-(2-Amino-acetylamino)-2-(4-fluoro-phenyl)...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070672(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070657(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070654(2-[(S)-1-(2-Amino-acetylamino)-2-(4-fluoro-phenyl)...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070675(2-[(S)-1-(3-Amino-propionylamino)-2-(4-fluoro-phen...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070663(2-[(S)-1-Amino-2-(4-fluoro-phenyl)-ethyl]-thiazole...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070667(2-[(S)-1-(2-Amino-3-methyl-butyrylamino)-2-(4-meth...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070658(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070661(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070666(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070665(2-[(S)-1-Acetylamino-2-(4-fluoro-phenyl)-ethyl]-5-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070671(2-[(S)-1-(2,3-Diamino-propionylamino)-2-(4-fluoro-...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070678(5-Methyl-2-[(S)-1-(2-methylamino-acetylamino)-2-ph...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031392((S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-h...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070664(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070659(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070655(1-{2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-ace...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50070660(2-[(S)-2-(4-Fluoro-phenyl)-1-(2-methylamino-acetyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50366501(CHEMBL1790239)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article
PubMed