Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50008175
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071250([(S)-3-((R)-2-Hydroxycarbamoylmethyl-decanoylamino...)
Affinity DataIC50: 11nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071248({(S)-3-[(R)-2-((R)-1-Hydroxycarbamoyl-ethyl)-decan...)
Affinity DataIC50: 21nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071246((2R,3R)-N*1*-Hydroxy-N*4*-[(S)-1-(2-methoxy-ethyl)...)
Affinity DataIC50: 30nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071256({(S)-3-[(R)-2-((R)-1-Hydroxycarbamoyl-ethyl)-4-met...)
Affinity DataIC50: 49nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071244((2R,3R)-N*1*-Hydroxy-2-(3-hydroxy-propyl)-3-isobut...)
Affinity DataIC50: 51nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071248({(S)-3-[(R)-2-((R)-1-Hydroxycarbamoyl-ethyl)-decan...)
Affinity DataIC50: 57nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071251([(S)-3-((2R,3R)-3-Hydroxycarbamoyl-2-isobutyl-hexa...)
Affinity DataIC50: 58nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071254((2R,3R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-(2-met...)
Affinity DataIC50: 83nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071254((2R,3R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-1-(2-met...)
Affinity DataIC50: 94nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071251([(S)-3-((2R,3R)-3-Hydroxycarbamoyl-2-isobutyl-hexa...)
Affinity DataIC50: 96nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071244((2R,3R)-N*1*-Hydroxy-2-(3-hydroxy-propyl)-3-isobut...)
Affinity DataIC50: 104nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071253((2R,3S)-N*1*-Hydroxy-N*4*-[(S)-1-(2-methoxy-ethyl)...)
Affinity DataIC50: 108nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071246((2R,3R)-N*1*-Hydroxy-N*4*-[(S)-1-(2-methoxy-ethyl)...)
Affinity DataIC50: 112nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071247((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-oxo-1-(2-p...)
Affinity DataIC50: 117nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071255([(S)-3-((R)-2-Hydroxycarbamoylmethyl-heptanoylamin...)
Affinity DataIC50: 129nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071249((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-oxo-1-(3-p...)
Affinity DataIC50: 140nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071256({(S)-3-[(R)-2-((R)-1-Hydroxycarbamoyl-ethyl)-4-met...)
Affinity DataIC50: 215nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071245([(S)-3-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pent...)
Affinity DataIC50: 225nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071243((R)-N*4*-Hydroxy-N*1*-[(S)-1-(2-methoxy-ethyl)-2-o...)
Affinity DataIC50: 250nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071247((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-oxo-1-(2-p...)
Affinity DataIC50: 518nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071255([(S)-3-((R)-2-Hydroxycarbamoylmethyl-heptanoylamin...)
Affinity DataIC50: 824nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071250([(S)-3-((R)-2-Hydroxycarbamoylmethyl-decanoylamino...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071249((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-oxo-1-(3-p...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071243((R)-N*4*-Hydroxy-N*1*-[(S)-1-(2-methoxy-ethyl)-2-o...)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071245([(S)-3-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pent...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071252((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-2-oxo-azepan...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071253((2R,3S)-N*1*-Hydroxy-N*4*-[(S)-1-(2-methoxy-ethyl)...)
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50071252((R)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-2-oxo-azepan...)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed