Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 50008293
LigandPNGBDBM50072197(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...)
Affinity DataIC50: 15nMAssay Description:Evaluated for the inhibition of [3H]rolipram binding to membrane-bound PDE4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072197(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...)
Affinity DataIC50: 16nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072197(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...)
Affinity DataIC50: 22nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072197(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...)
Affinity DataIC50: 25nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072197(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6...)
Affinity DataIC50: 30nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50072195(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethoxy-...)
Affinity DataIC50: 43nMAssay Description:Evaluated for the inhibition of [3H]rolipram binding to membrane-bound PDE4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50072194(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-butyl-6...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [3H]-rolipram binding to membrane-bound PDE4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072195(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethoxy-...)
Affinity DataIC50: 60nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072211(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 70nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072195(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethoxy-...)
Affinity DataIC50: 70nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072211(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 80nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072195(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethoxy-...)
Affinity DataIC50: 85nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072211(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 90nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072199(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2,6-dimet...)
Affinity DataIC50: 110nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072199(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2,6-dimet...)
Affinity DataIC50: 130nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072200(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 130nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072199(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2,6-dimet...)
Affinity DataIC50: 140nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50072200(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 145nMAssay Description:Evaluated for the inhibition of [3H]rolipram binding to membrane-bound PDE4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072200(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 200nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 200nMAssay Description:Evaluated for the inhibition of [3H]rolipram binding to membrane-bound PDE4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50072199(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2,6-dimet...)
Affinity DataIC50: 210nMAssay Description:Evaluated for the inhibition of [3H]rolipram binding to membrane-bound PDE4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 230nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072200(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 250nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072194(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-butyl-6...)
Affinity DataIC50: 300nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072194(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-butyl-6...)
Affinity DataIC50: 300nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072200(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 310nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 340nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072195(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethoxy-...)
Affinity DataIC50: 340nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072199(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2,6-dimet...)
Affinity DataIC50: 390nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072211(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 430nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 430nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072204(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethylsu...)
Affinity DataIC50: 440nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072209(3-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-(2-hydr...)
Affinity DataIC50: 500nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072204(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethylsu...)
Affinity DataIC50: 540nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072205(4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-cyclopropy...)
Affinity DataIC50: 540nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072205(4-(3,5-Bis-cyclopropylmethoxy-phenyl)-7-cyclopropy...)
Affinity DataIC50: 600nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072212(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-q...)
Affinity DataIC50: 630nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072206(4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6,7-dimethox...)
Affinity DataIC50: 650nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072210(4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-6-me...)
Affinity DataIC50: 650nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072212(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-q...)
Affinity DataIC50: 660nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072207([4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy-2...)
Affinity DataIC50: 700nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072204(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethylsu...)
Affinity DataIC50: 700nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072194(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-butyl-6...)
Affinity DataIC50: 720nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072206(4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6,7-dimethox...)
Affinity DataIC50: 800nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072212(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-ethyl-q...)
Affinity DataIC50: 850nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072206(4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6,7-dimethox...)
Affinity DataIC50: 900nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072198(4-(3,5-Diisopropoxy-phenyl)-6,7-dimethoxy-2-methyl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072208(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...)
Affinity DataIC50: 1.20E+3nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072194(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-2-butyl-6...)
Affinity DataIC50: 1.30E+3nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072203(2-[4-(3,5-Bis-cyclopropylmethoxy-phenyl)-6-methoxy...)
Affinity DataIC50: 1.30E+3nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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